公开(公告)号：US20170281546A1

公开(公告)日：2017-10-05

申请号：US15488616

申请日：2017-04-17

Applicant: VECTURA LIMITED

Inventor： David FARROW ,  Katie COGGINS

IPC: C07C303/42 ,  A61K45/06 ,  A61K31/138 ,  A61K31/167 ,  A61K31/439 ,  A61K31/137 ,  A61K31/58 ,  A61K31/185 ,  A61K9/16 ,  C07C309/14 ,  A61K31/40 ,  A61K9/00 ,  A61K31/4704

CPC classification number: A61K9/1617 ,  A61K9/0075 ,  A61K9/008 ,  A61K9/1682 ,  A61K31/137 ,  A61K31/138 ,  A61K31/167 ,  A61K31/185 ,  A61K31/40 ,  A61K31/439 ,  A61K31/4704 ,  A61K31/58 ,  A61K45/06 ,  C07C303/42 ,  C07C309/14 ,  A61K2300/00

Abstract: The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolisation.