公开(公告)号：US20210380915A1

公开(公告)日：2021-12-09

申请号：US17407392

申请日：2021-08-20

申请人： University of Maryland, Baltimore County

发明人： GOVIND RAO ,  YORDAN KOSTOV ,  MICHAEL TOLOSA ,  XUDONG GE ,  VIKASH KUMAR ,  Vida Rahmatnejad

IPC分类号： C12M1/24 ,  C12M3/00 ,  C12M1/04 ,  C12M1/00 ,  C12M1/34

摘要： The present invention relates to collapsible and/or foldable fermentation and/or culture vessels fabricated of an adjustable frame including sections of gas permeable material or in the alternative a non-rigid gas permeable polymeric container or bag fabricated of either a gas permeable or non-gas permeable material with the further benefit of more efficient inventory space and disposal space, wherein the gas permeable material or non-gas permeable material comprises an analyte or pH sensing material integrated or impregnated into at least one section of the material.

公开(公告)号：US20240318121A1

公开(公告)日：2024-09-26

申请号：US18668438

申请日：2024-05-20

申请人： UNIVERSITY OF MARYLAND, BALTIMORE COUNTY

发明人： Govind RAO ,  Vida Rahmatnejad ,  Xudong Ge ,  Vikash Kumar ,  Michael Tolosa

IPC分类号： C12M1/34 ,  C12M1/00

CPC分类号： C12M41/34 ,  C12M29/04 ,  C12M41/26

摘要： The present invention provides for systems and method for noninvasive measurement and monitoring of cell culture parameters including dissolved oxygen (DO), dissolved carbon dioxide (DCO2), and pH wherein there is no direct contact with the cell culture environment which is achieved by conducting the measurements and monitoring on the outside of the bioreactor through semi-permeable membranes incorporated into the system to enhance the process and eliminate the risk of contamination associated with invasive sensors.