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公开(公告)号:US20190321487A1
公开(公告)日:2019-10-24
申请号:US16469248
申请日:2017-12-14
Inventor: Raphael DARCY , Caitriona O'DRISCOLL , Meenakshi MALHOTRA
IPC: A61K47/69 , A61K47/62 , A61K47/61 , A61K31/7105
Abstract: A cyclodextrin-RNA conjugate is described in which the cyclodextrin molecule is conjugated at its glucosyl 6-, 2- or 3-positions, optionally via a linker, to at least one RNA molecule at the RNA 3′ terminal base. The at least one RNA molecule may be an siRNA molecule.