专利检索 ap:("UNIVERSITÄT ZÜRICH") AND inv:"Jason Philip HOLLAND" 第 1 页

1.

发明申请
PHOTOCHEMICALLY INDUCED CONJUGATION OF RADIOMETALS TO SMALL MOLECULES, PEPTIDES AND NANOPARTICLES IN A SIMULTANEOUS ONE-POT REACTION 有权

公开(公告)号：US20220017433A1

公开(公告)日：2022-01-20

申请号：US17295457

申请日：2019-11-21

申请人： UNIVERSITÄT ZÜRICH

发明人： Jason Philip HOLLAND , Malay PATRA

IPC分类号： C07B59/00 , A61K51/04

摘要： The invention relates to a method for labeling a target compound with a radiometal by photochemically induced conjugation. Furthermore, a chelating compound for use in said method is provided. The chelating compound is characterized by an arylazide moiety which can be photo-conjugated to a target compound and a chelator moiety which can be radiolabelled. The photo-conjugation and radiolabelling are both performed at basic pH performed in a simultaneous one-pot reaction.