公开(公告)号：US20170172928A1

公开(公告)日：2017-06-22

申请号：US15129714

申请日：2015-03-25

Applicant: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO

Inventor： David QUINTANAR GUERRERO ,  Laura Elizabeth HERNANDEZ RIZO

IPC: A61K9/28 ,  B05D5/00

CPC classification number: A61K9/284 ,  A61K9/2072 ,  A61K9/2826 ,  A61K9/2853 ,  A61K9/2866 ,  A61K2121/00 ,  B05D1/02 ,  B05D5/00 ,  B05D2258/02

Abstract: The present invention specifically refers to a pharmaceutical system for preparation of solid pharmaceutical forms for administering therapeutic substances improving their bioavailability; said system is particularly suitable for administering sensitive active principles by their proteinaceous nature or by being nucleic acids since polymeric excipients with good matrix and bioadhesion properties are used which together with the impermeability conferred by the applied coating make the prepared system a delivery form with excellent performance.

公开(公告)号：US20170232026A1

公开(公告)日：2017-08-17

申请号：US15503033

申请日：2015-08-12

Applicant: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO

Inventor： David QUINTANAR GUERRERO ,  Juan Pablo MARTINEZ LABAT ,  Susana Elisa MENDOZA ELVIRA ,  Gustavo VIDAL ROMERO ,  Victor Andres TRENADO HERNANDEZ

IPC: A61K31/7048 ,  A61K47/32 ,  A61K47/26 ,  A61K47/44 ,  A61K47/18 ,  A61K9/06 ,  A61K47/10

CPC classification number: A61K31/7048 ,  A61K9/0017 ,  A61K9/06 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44

Abstract: The invention relates to a pharmaceutical composition comprising: at least one antiparasitic active ingredient for providing the pharmacological therapeutic effect; an agent having bio-adhesive properties that helps to reduce the motility and reproduction of the parasites, increasing the period of time for which the product remains on the skin of the animals; an agent having permeation- or absorption-promoting properties that contributes to increasing the cutaneous permeability of the active ingredient; a surfactant agent that is absorbed in an oil-water interface, and as a result, the molecules of said surfactant agent form a kind of bridge between the polar phase (water) and the non-polar phase (oil), thereby making the transition between both phases less abrupt; an oil which will form the oily phase of the emulsion, and which will incorporate the active ingredient; and a neutralizing agent.