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公开(公告)号:US20190008963A1
公开(公告)日:2019-01-10
申请号:US16081526
申请日:2017-03-01
Applicant: Trustees of Boston University
Inventor: Xue HAN , Richie E. KOHMAN , Susie S. CHA
IPC: A61K41/00 , C07H21/00 , C07C247/10 , A61K47/54 , A61N5/06
Abstract: The invention provides oligonucleotide conjugates including a photolabile crosslinker attached to a cargo moiety, e.g., a therapeutic or diagnostic agent. The invention further provides reagents useful in the preparation of such conjugates and methods of their use.