公开(公告)号：US20180057534A1

公开(公告)日：2018-03-01

申请号：US15453369

申请日：2017-03-08

Applicant: Thrasos Therapeutics Inc.

Inventor： Roger Leger ,  Gilles Dube ,  Marie-Elaine Caruso ,  Jerome Rossert

IPC: C07K7/08 ,  A61K38/00

CPC classification number: C07K7/08 ,  A61K38/00

Abstract: Provided are novel peptides of Formula SEQ ID No. 1: (SEQ ID No. 1) J1CysX1X2X3X4X5X6ProX7ThrCysJ2J3(J4)s(J5)t; pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are which are effective inhibitors of light chains to uromodulin.

公开(公告)号：US09611297B1

公开(公告)日：2017-04-04

申请号：US15368260

申请日：2016-12-02

Applicant: Thrasos Therapeutics Inc.

Inventor： Roger Leger ,  Gilles Dube ,  Marie-Elaine Caruso ,  Jerome Rossert

IPC: C07K1/00 ,  C07K14/00 ,  C07K17/00 ,  A61K38/12 ,  C07K7/08 ,  A61K38/00

CPC classification number: C07K7/08 ,  A61K38/00

Abstract: Provided are novel peptides of Formula SEQ ID No. 1: J1CysX1X2X3X4X5X6ProX7ThrCysJ2J3(J4)s(J5)t;   (SEQ ID No. 1) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are effective inhibitors of light chains to uromodulin.