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公开(公告)号：US20230136166A1
公开(公告)日：2023-05-04
申请号：US17975066
申请日：2022-10-27
发明人： Kyle FORT , Alexander Makarov , Konstantin Ayzikov
摘要： Methods and systems for determining a measure of a rate of decay of an ion sample. Specifically, the present disclosure provides methods and apparatus for determining decay constants and cross-section measurements in parallel to mass measurement and decay time correction. The disclosure particularly relates to methods and apparatus for performing Fourier transform mass spectrometry (FTMS).
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公开(公告)号：US20240355608A1
公开(公告)日：2024-10-24
申请号：US18641183
申请日：2024-04-19
CPC分类号： H01J49/24 , G01N30/72 , H01J49/0009 , H01J49/26
摘要： Mass spectrometry systems for performing mass analysis on ion samples include a vacuum region comprising a mass analyser configured to provide a detection signal for the ion sample. A turbomolecular pump is configured to maintain the vacuum region at a vacuum pressure and a controller is configured to control the pressure within the mass analyser to control the rate of decay over time of the detection signal for the ion sample by: controlling a pumping speed of the turbomolecular pump. The turbomolecular pump can be configured to maintain the vacuum region at a first pressure when the mass analyser is being operated in a mass analysis mode of operation and a second pressure when the mass analyser is being operated in a collision cross section analysis mode of operation, wherein the second pressure is greater than the first pressure.
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公开(公告)号：US20230282471A1
公开(公告)日：2023-09-07
申请号：US18095860
申请日：2023-01-11
发明人： Hamish STEWART , Alexander MAKAROV , Konstantin AYZIKOV , Dmitry GRINFELD , Kyle FORT , Tabiwang ARREY , Matthias BIEL
CPC分类号： H01J49/421 , H01J49/062
摘要： A method of operating an instrument which comprises a first and second ion stores, comprising determining whether a target accumulation time for the second ion store is greater than a threshold accumulation time. When the target accumulation time is less than the threshold accumulation time, ions are accumulated within the second ion store using an accumulation time that is based on the target accumulation time. When the target accumulation time is greater than the threshold accumulation time, ions are accumulated within the first ion store using a first accumulation time that is based on a difference between the target accumulation time and the threshold accumulation time, the ions accumulated in the first ion store are passed to the second ion store, and further ions are accumulated within the second ion store using a second accumulation time that is based on the threshold accumulation time.
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