专利检索 ap:("The University of Chicago" OR "NorthShore University HealthSystem") AND inv:"Mitchell POSNER" 第 1 页

1.

发明公开
MOLECULAR SUBTYPING OF COLORECTAL LIVER METASTASES TO PERSONALIZE TREATMENT APPROACHES 审中-公开

公开(公告)号：US20240175093A1

公开(公告)日：2024-05-30

申请号：US18552414

申请日：2022-03-25

申请人： The University of Chicago , NorthShore University HealthSystem

发明人： Sean PITRODA , Mitchell POSNER , Ralph WEICHSELBAUM , Mark TALAMONTI

IPC分类号： C12Q1/6886 , C12Q1/686 , G16B25/10 , G16H50/20

CPC分类号： C12Q1/6886 , C12Q1/686 , G16B25/10 , G16H50/20 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178

摘要： Methods, assays, and compositions for identifying molecular subtypes of metastatic cancer are disclosed. Methods include determining expression levels of genes and/or miRNAs in a sample of metastatic tissue and identifying the molecular subtype of the metastasis based on the determined expression levels using a neural network-based classifier. Methods may further include providing a prognosis and making treatment decision based on the molecular subtype of the metastasis.