公开(公告)号：US20230020499A1

公开(公告)日：2023-01-19

申请号：US17787161

申请日：2020-12-24

申请人： The University Of Tokyo

发明人： Shoji Takeuchi ,  Yuya Morimoto ,  Byeongwook Jo ,  Minghao Nie ,  Ai Tajima

IPC分类号： C12N5/00 ,  C12N5/071 ,  C12N5/077

摘要： A method of producing a 3D tissue composite, comprising: a preparation step in which a multiple number of sheet-shaped first structures containing first cells are prepared, wherein at least one of the multiple number of first structures holds a second structure containing second cells; a stacking step in which the multiple number of first structures are stacked to form a 3D composite; and a culturing step in which the 3D composite is cultured to form a 3D tissue composite containing first tissues formed from the first cells and second tissues formed from the second cells.