Method of identifying cosmetic agents for moisturizing skin

    公开(公告)号:US11035851B2

    公开(公告)日:2021-06-15

    申请号:US15590598

    申请日:2017-05-09

    Abstract: Methods of identifying potential skin moisturizing actives for the treatment of dry skin and method of formulating a moisturizing skin care composition using actives identified by the method. Moisturizing agents can be identified by comparing the transcriptional profile of a skin tissue sample contacted by a test agent to a negative or positive control to determine if the regulation of certain genes corresponds to the appropriate direction of regulation indicated by the control. Agents identified as skin moisturizing agents can then be incorporated into a skin moisturizing composition.

    Composition for enhancing hair fiber properties

    公开(公告)号:US10603261B2

    公开(公告)日:2020-03-31

    申请号:US16434858

    申请日:2019-06-07

    Abstract: A hair conditioning composition comprising from about 0.1% to about 20% of a lipid being one or more unsaturated fatty material selected from a group consisting of an unsaturated fatty acid; an unsaturated fatty alcohol; an unsaturated amine; an unsaturated amide; and an unsaturated phospholipid; wherein the molecule of said unsaturated fatty material comprises a linear or branched carbon chain with 8 to 24 carbon atoms, and one carbon-carbon double bond in a position of the said carbon chain between position C3 and position omega for the unsaturated fatty acid or unsaturated amide and between position C2 and position omega for the unsaturated fatty alcohol, unsaturated amine or unsaturated phospholipid and wherein the LogP of said unsaturated fatty material is less than 7; and 0.1% to 20% of one or more lipid enhancing agent selected from the group comprising of a fatty acid monoester of a polyol wherein the molecule of the fatty acid component of such monoester contains a linear or branched carbon chain with 10 to 22 carbon atoms and wherein the fatty acid monoester of a polyol has a logP of less than 7; a saturated fatty alcohol wherein the molecule of the fatty alcohol contains a linear or branched carbon chain with 8 to 22 carbon atoms; an ester of a saturated fatty alcohol wherein the molecule of said ester contains 10 to 44 total carbon atoms; an alcohol wherein the molecule of such alcohol contains an aromatic ring.

    COMPOSITION FOR ENHANCING HAIR FIBER PROPERTIES

    公开(公告)号:US20190282474A1

    公开(公告)日:2019-09-19

    申请号:US16434858

    申请日:2019-06-07

    Abstract: A hair conditioning composition comprising from about 0.1% to about 20% of a lipid being one or more unsaturated fatty material selected from a group consisting of an unsaturated fatty acid; an unsaturated fatty alcohol; an unsaturated amine; an unsaturated amide; and an unsaturated phospholipid; wherein the molecule of said unsaturated fatty material comprises a linear or branched carbon chain with 8 to 24 carbon atoms, and one carbon-carbon double bond in a position of the said carbon chain between position C3 and position omega for the unsaturated fatty acid or unsaturated amide and between position C2 and position omega for the unsaturated fatty alcohol, unsaturated amine or unsaturated phospholipid and wherein the LogP of said unsaturated fatty material is less than 7; and 0.1% to 20% of one or more lipid enhancing agent selected from the group comprising of a fatty acid monoester of a polyol wherein the molecule of the fatty acid component of such monoester contains a linear or branched carbon chain with 10 to 22 carbon atoms and wherein the fatty acid monoester of a polyol has a logP of less than 7; a saturated fatty alcohol wherein the molecule of the fatty alcohol contains a linear or branched carbon chain with 8 to 22 carbon atoms; an ester of a saturated fatty alcohol wherein the molecule of said ester contains 10 to 44 total carbon atoms; an alcohol wherein the molecule of such alcohol contains an aromatic ring.

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