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公开(公告)号：US20200317648A1
公开(公告)日：2020-10-08
申请号：US16861075
申请日：2020-04-28
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10544117B2
公开(公告)日：2020-01-28
申请号：US15510152
申请日：2015-09-10
IPC分类号： C07D405/12 , A61K31/496 , C07D307/33 , C07D307/94 , C07D405/06
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10239868B2
公开(公告)日：2019-03-26
申请号：US15716752
申请日：2017-09-27
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10676464B2
公开(公告)日：2020-06-09
申请号：US16411534
申请日：2019-05-14
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US11897870B2
公开(公告)日：2024-02-13
申请号：US16861075
申请日：2020-04-28
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
CPC分类号： C07D405/12 , C07D307/33 , C07D307/94 , C07D405/06
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US20220306596A1
公开(公告)日：2022-09-29
申请号：US17517166
申请日：2021-11-02
IPC分类号： C07D307/33 , C07D307/94 , C07D405/06 , C07D405/12 , C07D307/28 , C07D405/14
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US20170298037A1
公开(公告)日：2017-10-19
申请号：US15510152
申请日：2015-09-10
IPC分类号： C07D307/33 , C07D307/94 , C07D405/06 , C07D405/12
CPC分类号： C07D307/33 , C07D307/28 , C07D307/94 , C07D405/06 , C07D405/12 , C07D405/14
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US10287274B2
公开(公告)日：2019-05-14
申请号：US15716773
申请日：2017-09-27
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US09802924B2
公开(公告)日：2017-10-31
申请号：US14774961
申请日：2014-03-11
IPC分类号： C07D405/12 , C07D405/06 , C07D307/94 , C07D307/33
CPC分类号： C07D405/12 , C07D307/33 , C07D307/94 , C07D405/06
摘要： Pharmaceiiticai compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
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公开(公告)号：US20220133713A1
公开(公告)日：2022-05-05
申请号：US17347253
申请日：2021-06-14
发明人： Daniel J. Canney , Benjamin E. Blass , Rong Gao , Kevin Blattner
IPC分类号： A61K31/496 , C07D405/12 , C07D405/06 , C07D405/14 , C07D417/12 , C07D307/94 , C07D413/12 , C07D405/02 , C07D307/33 , A61P35/00 , A61K31/4525 , A61K31/4709 , A61K31/4725
摘要： Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of sigma-2 receptor activity.
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