公开(公告)号：US20230322647A1

公开(公告)日：2023-10-12

申请号：US18042752

申请日：2021-08-22

申请人： Technion Research & Development Foundation Ltd.

发明人： Graham DE RUITER ,  Subhash GARHWAL

IPC分类号： C07C5/25 ,  C07B59/00 ,  C07F15/02 ,  B01J31/24 ,  B01J31/22 ,  B01J31/12

CPC分类号： C07C5/2575 ,  C07B59/00 ,  C07F15/02 ,  B01J31/2452 ,  B01J31/2273 ,  B01J2231/32 ,  C07B2200/05 ,  C07C2523/745 ,  B01J2531/842 ,  B01J2531/0244 ,  B01J2231/42 ,  B01J31/121

摘要： The present invention provides PCNHCP pincer metal complexes, which are useful as catalysts in various chemical reactions such as hydrogen isotope exchange (HIE) in C(sp3)-H and/or C(sp2)-H bond of an organic compound, e.g., a pharmaceutically active compound; hydroboration of alkynes with excellent selectivity; and alkene isomerization with high stereo- and regioselectivity.