公开(公告)号：US20240329053A1

公开(公告)日：2024-10-03

申请号：US18293087

申请日：2022-08-02

Applicant: TZARTOS NEURODIAGNOSTICS

Inventor： John TZARTOS ,  Socrates TZARTOS

IPC: G01N33/68 ,  G01N1/30

CPC classification number: G01N33/6854 ,  G01N1/30 ,  G01N33/6893 ,  G01N2001/305

Abstract: Cell-based method for detecting antibodies against subunits of the neuronal nicotinic acetylcholine receptors in a subject is disclosed. The method comprises steps of



engineering cells to express at least one protein;
optionally, culturing said cells with at least one substance;
exposing said cells to body fluid or tissue from subject; and
detecting a reaction between at least one protein and antibodies found in body fluid or tissue,
obtaining a diagnosis for the patient.




A kit is also disclosed for detecting antibodies against subunits of the nicotinic acetylcholine receptors in a subject. The kit comprises cells expressing at least one protein; at least one medium for cell culture, at least one buffer for cell culture; and optionally, at least one substance.