公开(公告)号：US20170326230A1

公开(公告)日：2017-11-16

申请号：US15529668

申请日：2015-12-01

申请人： TRANSGENE SA

发明人： Mélina CHASLE

IPC分类号： A61K39/275 ,  A61K47/26 ,  A61K9/08 ,  A61K9/00 ,  A61K39/12 ,  A61K47/10 ,  A61K47/18

摘要： The present invention relates to liquid formulations of poxvirus, in particular vaccinia virus, stable during storage. Such stable liquid formulations comprise a) a poxvirus, preferably a vaccinia virus, b) a pharmaceutically acceptable buffer, c) a monovalent salt, d) a pharmaceutically acceptable disaccharide or sugar alcohol, and e) a pharmaceutically acceptable chelating agent, wherein the pH of the formulation is comprised between 6.5 and 8.5.