公开(公告)号：US20150024416A1

公开(公告)日：2015-01-22

申请号：US14380074

申请日：2013-02-15

Applicant: THE BINDING SITE GROUP LIMITED ,  THE UNIVERSITY OF WARWICK

Inventor： Stephen Harding ,  Richard Hughes ,  Anne Bevins ,  Richard Keir ,  Michael Chappell ,  Neil Evans ,  Colin Hutchinson

IPC: G01N33/68

CPC classification number: G01N33/6857 ,  G01N2800/50

Abstract: The invention provides a method of estimating free light chain production (FLC) in a subject comprising (i) determining an amount of FLC in a sample from the subject; and (ii) correcting the amount of FLC in the sample for FLC cleared from the source of the sample by glomerular filtration and by reticuloendothelial (RE) clearance.

Abstract translation: 本发明提供一种估计受试者中游离轻链产生（FLC）的方法，包括（i）确定来自受试者的样品中FLC的量; 和（ii）校正通过肾小球滤过和网状内皮（RE）清除从样品来源清除的FLC样品中FLC的量。