PREPARATION AND USE OF A REACTIVE SOLID SUPPORT SURFACE
    1.
    发明申请
    PREPARATION AND USE OF A REACTIVE SOLID SUPPORT SURFACE 有权
    反应性固体支持表面的制备和使用

    公开(公告)号:US20100041127A1

    公开(公告)日:2010-02-18

    申请号:US12581431

    申请日:2009-10-19

    IPC分类号: C07K17/02 C12M1/34

    摘要: A method of preparing a protein-resistant reactive solid support surface is disclosed. The method comprises the steps of providing a solid support having a hydrogel coating with a plurality of binding elements, coupling a protein resistant compound to the hydrogel via a first fraction of the binding elements, and coupling at least one binding agent to the hydrogel via a second fraction of the binding elements, whereby the protein resistant compound and the at least one binding agent are co-immobilized to the hydrogel. Also the use of the reactive surface in analysis, such as immunogenicity assays, is disclosed.

    摘要翻译: 公开了一种制备蛋白质抗性活性固体支持物表面的方法。 该方法包括以下步骤:提供具有多个结合元件的水凝胶涂层的固体支持物,通过结合元件的第一部分将蛋白质抗性化合物偶联至水凝胶,以及通过经由 结合元件的第二部分,其中蛋白质抗性化合物和至少一种结合剂共同固定在水凝胶上。 还公开了分析中的反应性表面的使用,例如免疫原性测定法。