公开(公告)号：US20230158284A1

公开(公告)日：2023-05-25

申请号：US17915693

申请日：2021-04-01

申请人： T.J.Smith and Nephew,Limited

发明人： Maria Aspioti ,  Michael Brown ,  Varuni Rachindra Brownhill ,  Anthony Colin Dagger ,  Mark John Ellerington ,  Daniel James Fitzgerald ,  Nicholas Charlton Fry ,  Latifa Giaffar ,  Victoria Jody Hammond ,  Edward Yerbury Hartwell ,  Neill John Rawson ,  Anna Elizabeth Smith ,  Liam Thomson ,  Iain Webster

IPC分类号： A61M35/00 ,  A61F13/02 ,  A61L15/44 ,  A61L15/18 ,  A61L15/20

CPC分类号： A61M35/30 ,  A61F13/0206 ,  A61F13/0223 ,  A61L15/18 ,  A61L15/20 ,  A61L15/44 ,  A61M2202/0275

摘要： Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The nitric oxide source layer may include a nitrite salt. Nitrite ions of the nitric oxide source layer may react with the acidic groups of the activating layer to generate nitric oxide. The activating layer may include a window at the center, and a central absorbent material may be positioned at the window. Various separating layers may also be incorporated into the dressing to control the interaction between activating layer and nitric oxide source layer.