公开(公告)号：US20170268057A1

公开(公告)日：2017-09-21

申请号：US15329855

申请日：2015-07-30

Applicant: Sutter West Bay Hospitals

Inventor： Gregory J. Tranah ,  Steven R. Cummings ,  Shana M. Katzman

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/156 ,  G06F19/325 ,  G16B20/00 ,  G16B50/00 ,  G16H50/30

Abstract: The disclosure provides methods, algorithms and compositions for determining the risk, diagnosis or prognosis of mitochondrial-associated disease and disorders by determining the mutational heteroplasmic burden in a subject.

公开(公告)号：US11332792B2

公开(公告)日：2022-05-17

申请号：US15329855

申请日：2015-07-30

Applicant: Sutter West Bay Hospitals

Inventor： Gregory J. Tranah ,  Steven R. Cummings ,  Shana M. Katzman

IPC: C12Q1/68 ,  C12Q1/6883 ,  G16H20/00 ,  G16H70/20 ,  G16B20/20 ,  G16B20/00 ,  G16B50/00 ,  G16H50/30

Abstract: The disclosure provides methods, algorithms and compositions for determining the risk, diagnosis or prognosis of mitochondrial-associated disease and disorders by determining the mutational heteroplasmic burden in a subject.