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公开(公告)号：US20180214107A1
公开(公告)日：2018-08-02
申请号：US15879126
申请日：2018-01-24
Applicant: Straxcorp Pty Ltd
Inventor： Roger ZEBAZE , Eleanor Jean MACKIE , Anne BOHTE , Aloys MBALA , Ali GHASEMZADEH , Ego SEEMAN
CPC classification number: A61B6/505 , A61B6/032 , A61B6/5205 , G06T7/0012 , G06T7/12 , G06T7/70 , G06T11/003 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/20104 , G06T2207/30008 , G06T2207/30096
Abstract: A method for analysing a sample comprising a first material and a second material of generally different densities and having a junction therebetween, the method comprising defining a region of interest in a cross sectional image of at least a portion of the sample that includes said junction, determining a density profile of the sample within the region of interest and crossing the junction, determining a representative density of said second material, and analysing said sample using said junction used to distinguish said first and second materials.
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公开(公告)号：US20150262387A1
公开(公告)日：2015-09-17
申请号：US14720004
申请日：2015-05-22
Applicant: StraxCorp Pty Ltd
Inventor： Roger ZEBAZE , Eleanor Jean MACKIE , Anne BOHTE , Aloys MBALA , Ali GHASEMZADEH , Ego SEEMAN
CPC classification number: A61B6/505 , A61B6/032 , A61B6/5205 , G06T7/0012 , G06T7/12 , G06T7/70 , G06T11/003 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/20104 , G06T2207/30008 , G06T2207/30096
Abstract: A computer-implemented method for analysing a sample comprising a first material and a second material of generally different densities and having a junction therebetween. The method comprises: defining automatically a plurality of regions of interest within an image of the sample, each of said regions of interest having a width of one or more voxels or pixels; determining respective density, intensity or attenuation profiles within the regions of interest; determining a location of said junction including defining a first reference point within one of said first and second materials and employing the first reference point as current reference point, and (i) determining a closest point to said current reference point that is on said respective profile and in the other of said first and second materials to that of the current reference point; (ii) locating a greatest difference in values of the respective profile between an adjacent peak and trough in a segment of the respective profile between said current reference point and said closest point; and (iii) locating a point of inflexion in said segment.
Abstract translation: 一种用于分析样品的计算机实现的方法，所述样品包括第一材料和具有大致不同密度的第二材料并且在其间具有接合部。 该方法包括：在样本的图像内自动定义多个感兴趣区域，所述感兴趣区域中的每一个具有一个或多个体素或像素的宽度; 确定感兴趣区域内的相应密度，强度或衰减曲线; 确定所述连接点的位置，包括在所述第一和第二材料之一内定义第一参考点，并采用第一参考点作为当前参考点，以及（i）确定位于所述相应轮廓上的所述当前参考点的最近点 而在另一种所述的第一和第二种材料中，与当前的参考点相同; （ii）在所述当前参考点和所述最近点之间的相应轮廓的段中的相邻峰和谷之间确定相应轮廓的值的最大差异; 和（iii）在所述段中定位拐点。
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公开(公告)号：US20170119333A1
公开(公告)日：2017-05-04
申请号：US15398116
申请日：2017-01-04
Applicant: Straxcorp Pty Ltd
Inventor： Roger ZEBAZE , Eleanor Jean MACKIE , Anne BOHTE , Aloys MBALA , Ali GHASEMZADEH , Ego SEEMAN
CPC classification number: A61B6/505 , A61B6/032 , A61B6/5205 , G06T7/0012 , G06T7/12 , G06T7/70 , G06T11/003 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/20104 , G06T2207/30008 , G06T2207/30096
Abstract: A method for quantifying the effects of a treatment of a subject, comprising: analysing a sample of the subject, the sample comprising a material of interest and at least one adjacent material that is generally adjacent to the material of interest, the material of interest having a generally different density from the adjacent material. The analysing comprises: (i) automatically defining a plurality of regions of interest within an image of the sample that includes a junction between the material of interest and the adjacent material, each of said regions of interest having a width of one or more pixels or voxels; (ii) determining respective profiles of density, intensity or attenuation within the regions of interest, each of the respective profiles crossing the junctions between the material of interest and the adjacent material; (iii) automatically identifying the material of interest in the profiles; (iv) analysing said profiles by automatically defining, for each of said profiles, a series of sections of said respective profile, each of said sections comprising at least one S-like portion of the respective profile, the S-like portion containing the junction between the material of interest and the adjacent material; and (v) locating the junction in each of the S-like portions, including: (a) identifying the greatest difference in values of the respective profile between an adjacent peak and trough in a segment of the respective profile that includes at least some of the material of interest and at least some of the adjacent material; and (b) locating a point of inflexion in said segment. This method may also be employed in a method of treatment of a disease in a subject.
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公开(公告)号：US20160296188A1
公开(公告)日：2016-10-13
申请号：US15191079
申请日：2016-06-23
Applicant: StraxCorp Pty Ltd
Inventor： Roger ZEBAZE , Eleanor Jean MACKIE , Anne BOHTE , Aloys MBALA , Ali GHASEMZADEH , Ego SEEMAN
CPC classification number: A61B6/505 , A61B6/032 , A61B6/5205 , G06T7/0012 , G06T7/12 , G06T7/70 , G06T11/003 , G06T2200/24 , G06T2207/10081 , G06T2207/10088 , G06T2207/20104 , G06T2207/30008 , G06T2207/30096
Abstract: A computer-implemented system and method for analysing a sample comprising a material of interest and at least first and second adjacent materials each generally adjacent to the material of interest, the material of interest having a generally different density from the at least first and second adjacent materials. The method comprises automatically defining a plurality of regions of interest within an image of the sample that includes a junction between the material of interest and the first adjacent material and a junction between the material of interest and the second adjacent material, each of the regions of interest having a width of one or more pixels or voxels; determining respective profiles of density, intensity or attenuation within the regions of interest, each of the respective profiles crossing the respective junctions; automatically identifying the material of interest in the density profile; analysing the profiles by automatically defining, for each of the profiles, a series of sections of the respective profile, each of the sections comprising at least first and second S-like portions of the respective profile, the first portion containing the junction between the material of interest and the first adjacent material, the second portion containing the junction between the material of interest and the second adjacent material; and locating the junction in each of the first portions, including: identifying the greatest difference in values of the respective profile between an adjacent peak and trough in a segment of the respective profile that includes at least some of the material of interest and at least some of the first adjacent material; and locating a point of inflexion in the segment.
Abstract translation: 一种用于分析样品的计算机实现的系统和方法，所述样品包括感兴趣的材料和至少第一和第二相邻材料，每个材料通常与感兴趣的材料相邻，感兴趣的材料具有与至少第一和第二相邻 材料 该方法包括在样本的图像内自动定义多个感兴趣区域，该多个区域包括感兴趣的材料和第一相邻材料之间的连接点以及感兴趣材料和第二相邻材料之间的连接点，每个区域 兴趣具有一个或多个像素或体素的宽度; 确定感兴趣区域内的密度，强度或衰减的各个轮廓，各个轮廓中的每一个与相应的交叉点交叉; 自动识别密度分布中感兴趣的材料; 通过为每个轮廓自动定义相应轮廓的一系列部分来分析轮廓，每个部分包括相应轮廓的至少第一和第二S形部分，第一部分包含材料之间的连接部 感兴趣的和第一相邻材料，第二部分包含感兴趣的材料和第二相邻材料之间的连接点; 以及将所述结点定位在所述第一部分中的每一个中，包括：识别所述相应轮廓的段中的相邻峰和波谷之间的相应轮廓的值中的最大差值，所述相关轮廓包括至少一些所述材料和至少一些 的第一相邻材料; 并在分段中定位拐点。
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