公开(公告)号：US11981753B2

公开(公告)日：2024-05-14

申请号：US17726604

申请日：2022-04-22

Applicant: ShangPharma Innovation Inc.

Inventor： Yvonne Angell ,  Yu Wu ,  Yan Wang ,  Weimin Liu ,  Kin Chiu Fong ,  Jie Wen ,  Yonghan Hu

IPC: A61K47/60 ,  A61P35/04 ,  C07K7/06 ,  A61K38/00

CPC classification number: C07K7/06 ,  A61K47/60 ,  A61P35/04 ,  A61K38/00

Abstract: Disclosed are a peptide compound and an application thereof, and a composition containing the peptide compound. The present invention provides a peptide compound YA-156, and a pharmaceutically acceptable salt, a tautomer, a solvate, a crystal form or a prodrug thereof. The compound has good stability and good activity for Kiss1R.
Palm-PEG8-Gly-Gly-(D-Tyr)-Hyp-Asn-Thr-Phe-azaGly-Leu-Arg (Me)-Trp-NH2