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公开(公告)号：US09346844B2
公开(公告)日：2016-05-24
申请号：US13950716
申请日：2013-07-25
Applicant: Scinopharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Shang-Hong Chen , Li-Ting Wang , Wen-Li Shih , Yuan-Xiu Liao
IPC: C07H1/00 , C07H5/04 , C07H15/04 , C07H15/203
CPC classification number: C07H15/04 , C07H1/00 , C07H5/04 , C07H15/203
Abstract: The present invention provides novel processes for the preparation of Fondaparinux sodium by using the compound of formula ABC5 In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.
Abstract translation: 本发明提供了通过使用式ABC5化合物制备磺达肝素钠的新方法。在一些实施方案中，还提供了用于合成磺达肝素钠的中间体。
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Patent Agency Ranking
公开(公告)号：US20150005489A1
公开(公告)日：2015-01-01
申请号：US14315642
申请日：2014-06-26
Applicant: ScinoPharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Hsiao-Ping Fang , Ming-Feng Wu , Yu-Sheng Chang
CPC classification number: C07J43/003 , C07J1/0011 , C07J31/006 , Y02P20/55
Abstract: The present invention provides intermediates for preparing abiraterone, and processes for preparing abiraterone and intermediates thereof. The intermediates include a compound of formula (IV): wherein R represents a hydroxy-protecting group.
Abstract translation: 本发明提供了制备阿维酮的中间体，以及制备阿维酮及其中间体的方法。 中间体包括式（IV）的化合物：其中R表示羟基保护基。
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公开(公告)号：US20150031866A1
公开(公告)日：2015-01-29
申请号：US13950745
申请日：2013-07-25
Applicant: Scinopharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Shang-Hong Chen , Li-Ting Wang , Wen-Li Shih , Yuan-Xiu Liao
IPC: C07H15/04
Abstract: The present invention provides improved processes of preparing Fondaparinux sodium comprising converting a compound of formula ABCDE4 to Fondaparinux sodium at a reaction pH of no more than about 9.0. In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.
Abstract translation: 本发明提供了制备磺达肝素钠的改进方法，包括在不超过约9.0的反应pH下将式ABCDE4化合物转化成磺达肝素钠。 在一些实施方案中，还提供了合成磺达肝素钠的中间体。
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公开(公告)号：US10072039B2
公开(公告)日：2018-09-11
申请号：US13950745
申请日：2013-07-25
Applicant: Scinopharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Shang-Hong Chen , Li-Ting Wang , Wen-Li Shih , Yuan-Xiu Liao
Abstract: The present invention provides improved processes of preparing Fondaparinux sodium comprising converting a compound of formula ABCDE4 to Fondaparinux sodium at a reaction pH of no more than about 9.0. In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.
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公开(公告)号：US09556218B2
公开(公告)日：2017-01-31
申请号：US14315642
申请日：2014-06-26
Applicant: ScinoPharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Hsiao-Ping Fang , Ming-Feng Wu , Yu-Sheng Chang
CPC classification number: C07J43/003 , C07J1/0011 , C07J31/006 , Y02P20/55
Abstract: The present invention provides intermediates for preparing abiraterone, and processes for preparing abiraterone and intermediates thereof. The intermediates include a compound of formula (IV): wherein R represents a hydroxy-protecting group.
Abstract translation: 本发明提供了制备阿维酮的中间体，以及制备阿维酮及其中间体的方法。 中间体包括式（IV）的化合物：其中R表示羟基保护基。
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公开(公告)号：US20150031865A1
公开(公告)日：2015-01-29
申请号：US13950716
申请日：2013-07-25
Applicant: Scinopharm Taiwan, LTD.
Inventor： Lung-Huang Kuo , Shang-Hong Chen , Li-Ting Wang , Wen-Li Shih , Yuan-Xiu Liao
IPC: C07H15/04 , C07H15/203
CPC classification number: C07H15/04 , C07H1/00 , C07H5/04 , C07H15/203
Abstract: The present invention provides novel processes for the preparation of Fondaparinux sodium by using the compound of formula ABC5 In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided.
Abstract translation: 本发明提供了通过使用式ABC5化合物制备磺达肝素钠的新方法。在一些实施方案中，还提供了用于合成磺达肝素钠的中间体。
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