公开(公告)号：US20150087032A1

公开(公告)日：2015-03-26

申请号：US14336945

申请日：2014-07-21

Applicant: Samsung Electronics Co., Ltd.

Inventor： Young-kyoung PARK ,  Chang-duk Kang ,  Ji-yoon Song ,  Ju-young Lee ,  Seung-hyun Lee ,  Kwang-myung Cho

IPC: C12P7/56 ,  C12P7/06

CPC classification number: C12P7/56 ,  C07K14/39 ,  C07K14/395 ,  C12P7/06 ,  Y02E50/17

Abstract: A genetically engineered yeast cell that produces a pyruvate-based metabolite from pyruvate, wherein activity of a mitochondrial pyruvate carrier (MPC) is reduced compared to a parent yeast cell and a method of producing the pyruvate-based metabolite using the yeast cell.

Abstract translation: 一种遗传工程酵母细胞，其从丙酮酸生成基于丙酮酸的代谢物，其中与亲本酵母细胞相比，线粒体丙酮酸载体（MPC）的活性降低，以及使用酵母细胞产生基于丙酮酸的代谢物的方法。

公开(公告)号：US20140030781A1

公开(公告)日：2014-01-30

申请号：US13952410

申请日：2013-07-26

Applicant: Samsung Electronics Co., Ltd.

Inventor： Kyu-sang LEE ,  Young-min LEE ,  Woo-yong LEE ,  Hyun-min KOO ,  Jin-woo KIM ,  Young-kyoung PARK ,  Jin-hwan PARK ,  Hwa-young CHO ,  Jae-chan PARK

IPC: C12P7/18 ,  C12N15/77

CPC classification number: C12P7/18 ,  C12N9/0006 ,  C12N15/52 ,  C12N15/77 ,  C12Y101/01037 ,  C12Y101/05004 ,  Y02P20/52

Abstract: A recombinantly modified Corynebacterium glutamicum microorganism with an improved 1,4-butanediol (1,4-BDO) productivity relative to an unmodified Corynebacterium glutamicum microorganism, wherein activity of an enzyme catalyzing a conversion reaction between malate and oxaloacetate is inactivated or reduced relative to an unmodified Corynebacterium glutamicum microorganism, as well as a method of making and using same.

Abstract translation: 相对于未修饰的谷氨酸棒杆菌微生物，具有改进的1,4-丁二醇（1,4-BDO）生产力的重组修饰的谷氨酸棒杆菌微生物，其中催化苹果酸和草酰乙酸之间的转化反应的酶的活性相对于 未经修饰的谷氨酸棒杆菌微生物，以及其制备和使用方法。