公开(公告)号：US20250059162A1

公开(公告)日：2025-02-20

申请号：US18723083

申请日：2022-12-22

Applicant: SUZHOU KINTOR PHARMACEUTICALS, INC.

Inventor： Zhaohui YANG ,  Songying LIU ,  Jie PAN ,  Dong CHEN ,  Ruo XU ,  Liandong MA ,  Youzhi TONG

IPC: C07D401/14 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/513 ,  A61K31/517 ,  A61K31/53 ,  A61P35/00 ,  C07D405/14 ,  C07D471/04 ,  C07D487/04 ,  C07D495/04

Abstract: Provided is a multi-protein degradation agent having an imide skeleton, which can degrade multiple proteins comprising c-Myc, GSPT1, CK1α and IKZF (1/2/3) proteins, and therefore can be used for treating diseases or disorders related thereto, such as cancer.