公开(公告)号：US20180140549A1

公开(公告)日：2018-05-24

申请号：US15580732

申请日：2016-06-08

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD

Inventor： Wen Wee MA ,  Alex ADJEI ,  Lynne BUI ,  Ronald HARNING ,  Ajay KHOPADE ,  Subhas BHOWMICK ,  Natarajan ARULSUDAR ,  Narendra LAKKAD

IPC: A61K9/10 ,  A61K31/337 ,  A61P35/00 ,  A61K9/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/32 ,  A61K47/28

CPC classification number: A61K9/10 ,  A61K9/0019 ,  A61K9/5123 ,  A61K9/5138 ,  A61K9/5146 ,  A61K31/337 ,  A61K47/10 ,  A61K47/12 ,  A61K47/28 ,  A61K47/32 ,  A61P35/00

Abstract: A method of treating patients suffering from carcinoma of intrahepatic or extra hepatic bile duct or gall bladder which is locally advanced or metastatic, by intravenously administering to the patient, paclitaxel in the form of a nanodispersion. The nanodispersion comprises particles with a mean particle size less than 300 nm and is free of polyoxyethylated castor oil and free of a protein.