公开(公告)号：US10159662B2

公开(公告)日：2018-12-25

申请号：US15767508

申请日：2016-12-08

Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.

Inventor： Yinong Xie ,  Zejin You ,  Zhiwen Deng ,  Jun Zhu ,  Ao Wang ,  Yan Feng ,  Dong Long ,  Hong Zeng ,  Hongmei Song ,  Qijun Ye ,  Wei Qi ,  Donghai Su ,  Lichun Wang ,  Jingyi Wang

IPC: A61K31/437 ,  A61P19/02 ,  A61P29/00 ,  A61P35/00 ,  A61P37/00 ,  A61K39/00 ,  A61K31/343 ,  A61K38/17 ,  A61K31/519

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

公开(公告)号：US11045455B2

公开(公告)日：2021-06-29

申请号：US16745206

申请日：2020-01-16

Applicant: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.

Inventor： Yinong Xie ,  Zejin You ,  Zhiwen Deng ,  Jun Zhu ,  Ao Wang ,  Yan Feng ,  Dong Long ,  Hong Zeng ,  Hongmei Song ,  Qijun Ye ,  Wei Qi ,  Donghai Su ,  Lichun Wang ,  Jingyi Wang

IPC: A61K31/437 ,  A61K31/519 ,  C07D487/04 ,  C07D471/04 ,  A61P37/00 ,  A61P19/02 ,  A61P29/00 ,  A61P35/00 ,  A61K31/343 ,  A61K38/17 ,  A61K39/00

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.