公开(公告)号：US20180133279A1

公开(公告)日：2018-05-17

申请号：US15573583

申请日：2016-05-12

申请人： SHANXI MOMENTUM PHARMACEUTICAL CO.,LTD.

发明人： Baoan WANG ,  Peng MAO

IPC分类号： A61K36/8968 ,  A61K36/8888 ,  A61K36/076 ,  A61K36/752 ,  A61K36/185 ,  A61K36/736 ,  A61K36/489 ,  A61K36/282 ,  A61K36/258 ,  A61K36/484 ,  A61P9/06

CPC分类号： A61K36/8968 ,  A61K36/076 ,  A61K36/185 ,  A61K36/258 ,  A61K36/282 ,  A61K36/484 ,  A61K36/489 ,  A61K36/736 ,  A61K36/752 ,  A61K36/8888 ,  A61K2236/00 ,  A61P9/06

摘要： The present invention provides an application of a combination of traditional Chinese medicine in the preparation of a potassium ion channel modulating agent. The combination of traditional Chinese medicine is made up of traditional Chinese medicine raw materials according to the following weight proportion: Coptidis Rhizoma250~450Sophorae Flavescentis150~350 Radix Pinelliae Rhizoma150~350Artemisiae Annuae Herba150~350 Poria150~450Ginseng Radix Et Rhizoma 65~265 Aurantii Fructus 65~265Ophiopogonis Radix150~350 Immaturus Dichroae Radix150~350Glycyrrhizae Radix Et 65~265 Nelumbinis Plumula10~70Rhizoma The combination of traditional Chinese medicine of the present invention could prolong the action potential interval of the myocardial cells, thereby prolong the refractory period of myocardial electrical activity. It has the function of inhibiting arrhythmia induced by excitatory reentry without toxic side effects. The invention provides a new medicine for the treatment of ventricular, atrial or ventricular arrhythmias, and it has a good application prospect. The invention is easy to be operated and suitable for large-scale production.