专利检索 ap:("SCINNOHUB PHARMACEUTICAL CO., LTD") AND inv:"Dewei ZHANG" 第 1 页

1.

发明公开
PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 审中-公开

公开(公告)号：US20240124443A1

公开(公告)日：2024-04-18

申请号：US18264310

申请日：2022-01-28

申请人： SCINNOHUB PHARMACEUTICAL CO., LTD

发明人： Anle YANG , Sen JI , Zhi WANG , Hao WANG , Dewei ZHANG , Xiao WANG , Huan SHEN , Jie XIANG , Jialing XIAN , Yan WANG , Xiao HU , Xiaodong ZHANG , Jun TANG

IPC分类号： C07D471/04 , A61P7/04 , C07D491/20

CPC分类号： C07D471/04 , A61P7/04 , C07D491/20

摘要： The present invention relates to a compound of formula (I) capable of inhibiting plasmin activity and having blood coagulation and hemostasis activity, and a pharmaceutically acceptable salt, hydrate, isomer, prodrug and mixture thereof, wherein R1 to R3 are as defined in the description.

2.

发明公开
METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 审中-公开

公开(公告)号：US20240228491A1

公开(公告)日：2024-07-11

申请号：US18557795

申请日：2022-04-28

申请人： SCINNOHUB PHARMACEUTICAL CO., LTD.

发明人： Anle YANG , Dewei ZHANG , Lijin DONG , Quanhong HE , Tao YI , Jiang MENG , Lin TIAN , Jie LIANG , Ze FENG , Kai HU , Xiaodong ZHANG , Yi ZHANG , Xi HU , Yanan HOU , Jun TANG

IPC分类号： C07D471/04 , A61K31/4375 , A61K31/444 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/502 , A61K31/517 , A61P35/00 , C07D519/00

CPC分类号： C07D471/04 , A61K31/4375 , A61K31/444 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/502 , A61K31/517 , A61P35/00 , C07D519/00

摘要： Disclosed are a methionine adenosyltransferase inhibitor represented by formula (I), a preparation method thereof and an application thereof in the pharmaceutical field, wherein R1, R2, R3 and A are as defined in the description and claims.

3.

发明申请
FLUORINE-CONTAINING HETEROCYCLIC DERIVATIVES WITH MACROCYCLIC STRUCTURE AND USE THEREOF 有权

公开(公告)号：US20230044722A1

公开(公告)日：2023-02-09

申请号：US17781167

申请日：2020-12-11

申请人： ScinnoHub Pharmaceutical Co., Ltd

发明人： Anle YANG , Haoxi HUANG , Tonghui CHEN , Jie LIANG , Dewei ZHANG , Jingen DENG , Hongbo LI , Junjie PU

IPC分类号： C07D498/22

摘要： Disclosed are a macrocyclic fluorine-containing heterocyclic derivative of formula (I), a preparation method thereof, and a use thereof in treatment of TRK kinase-mediated diseases.

4.

发明公开
PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 审中-公开

公开(公告)号：US20240300986A1

公开(公告)日：2024-09-12

申请号：US18260072

申请日：2021-12-30

申请人： SCINNOHUB PHARMACEUTICAL CO., LTD

发明人： Anle YANG , Sen JI , Zhi WANG , Hao WANG , Dewei ZHANG , Xiao WANG , Huan SHEN , Jie XIANG , Jialing XIAN , Yan WANG , Xiao HU , Xiaodong ZHANG , Jun TANG

IPC分类号： C07F9/6561 , A61K31/675 , A61P7/04

CPC分类号： C07F9/6561 , A61K31/675 , A61P7/04

摘要： A compound of formula (I) capable of inhibiting plasmin activity, delaying fibrinolysis, and having coagulation and hemostatic activity, pharmaceutically acceptable salts, hydrates, isomers, prodrugs and mixtures thereof, wherein X, and R1 to R5 are as defined in the description.