公开(公告)号：US07759647B2

公开(公告)日：2010-07-20

申请号：US11657155

申请日：2007-01-24

Applicant: Ron Grazioso ,  Mehmet Aykac

Inventor： Ron Grazioso ,  Mehmet Aykac

IPC: G01T1/164

CPC classification number: G01T1/249 ,  A61B6/037 ,  G01T1/1603 ,  G01T1/208 ,  G01T1/2985

Abstract: PET detector modules are provided within a multi-dimensional magnetic field, to confine the range of emitted positrons from an object being imaged to improve spatial resolution of reconstructed PET images. Each module includes a number of independent, optically isolated detectors. Each detector includes an array of scintillator crystals read out by an array of APDs (avalanche photodiodes).

Abstract translation: PET检测器模块设置在多维磁场内，以限制来自被成像对象的发射正电子的范围，以改善重建的PET图像的空间分辨率。 每个模块包括多个独立的光隔离探测器。 每个检测器包括由APD阵列（雪崩光电二极管）读出的闪烁体晶体阵列。

公开(公告)号：US20080173819A1

公开(公告)日：2008-07-24

申请号：US11657155

申请日：2007-01-24

Applicant: Ron Grazioso ,  Mehmet Aykac

Inventor： Ron Grazioso ,  Mehmet Aykac

IPC: G01T1/164

CPC classification number: G01T1/249 ,  A61B6/037 ,  G01T1/1603 ,  G01T1/208 ,  G01T1/2985

Abstract: PET detector modules are provided within a multi-dimensional magnetic field, to confine the range of emitted positrons from an object being imaged to improve spatial resolution of reconstructed PET images. Each module includes a number of independent, optically isolated detectors. Each detector includes an array of scintillator crystals read out by an array of APDs (avalanche photodiodes).

Abstract translation: PET检测器模块设置在多维磁场内，以限制来自被成像对象的发射正电子的范围，以改善重建的PET图像的空间分辨率。 每个模块包括多个独立的光隔离探测器。 每个检测器包括由APD阵列（雪崩光电二极管）读出的闪烁体晶体阵列。

公开(公告)号：US08330112B2

公开(公告)日：2012-12-11

申请号：US12558475

申请日：2009-09-11

Applicant: Mehmet Aykac ,  Michael Loope ,  Mark Musrock

Inventor： Mehmet Aykac ,  Michael Loope ,  Mark Musrock

IPC: G01T1/20

CPC classification number: G01T1/2006 ,  G01T1/00 ,  G01T1/1647 ,  G01T1/2002 ,  G01T7/005

Abstract: A method for improving timing response in light-sharing scintillation detectors is disclosed. The method includes detecting an event, by a plurality of photo sensors, from a scintillation crystal. The method then includes sampling and digitizing the photo sensor outputs by an analog-to-digital converter. Then the method includes correcting associated timing data, by a processor, for each of the photo sensor outputs based on a lookup table. The method then includes selectively time shifting the photo sensor outputs based on the lookup table to generate corrected photo sensor outputs. The method then includes summing the corrected photo sensor outputs by the processor. The method then includes generating an event time, by the processor, for the detected event based on the sum of the corrected photo sensor outputs.

Abstract translation: 公开了一种改善分光闪烁检测器中的时序响应的方法。 该方法包括通过多个光传感器从闪烁晶体检测事件。 该方法然后包括通过模数转换器对光传感器输出进行采样和数字化。 然后，该方法包括基于查找表，通过处理器为每个光传感器输出校正相关的定时数据。 该方法然后包括基于查找表选择性地时间偏移光传感器输出以产生校正的光传感器输出。 该方法然后包括由处理器对校正后的光传感器输出求和。 该方法然后包括由处理器基于校正的光传感器输出的总和产生检测到的事件的事件时间。

公开(公告)号：US08384037B2

公开(公告)日：2013-02-26

申请号：US12558394

申请日：2009-09-11

Applicant: Mehmet Aykac ,  Mark Musrock ,  Carlyle L. Reynolds

Inventor： Mehmet Aykac ,  Mark Musrock ,  Carlyle L. Reynolds

IPC: G01T1/20

CPC classification number: G01T1/00

Abstract: A method, disclosure relates to for improving detection of true coincidence events and differentiating them from events detected from scattered and random gamma photons, comprises receiving electromagnetic radiation at a plurality of photo detectors that was generated by a scintillating crystal impacted by a gamma photon, and processing data received at a subset of the plurality of photo detectors that are closer to a scintillating crystal, thereby improving a timing coincidence window for detecting a coincidence event.

Abstract translation: 一种方法，公开内容涉及用于改进真实重合事件的检测并将其与从散射和随机伽马光子中检测到的事件区分开来，包括在被伽马光子影响的闪烁晶体产生的多个光检测器上接收电磁辐射，以及 处理在更靠近闪烁晶体的多个光电检测器的子集处接收的数据，由此改善用于检测符合事件的定时重合窗口。

公开(公告)号：US07164136B2

公开(公告)日：2007-01-16

申请号：US10680015

申请日：2003-10-07

Applicant: Mehmet Aykac ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Mark S. Andreaco ,  Lars A. Eriksson ,  Charles W. Williams ,  Ronald Nutt

Inventor： Mehmet Aykac ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Mark S. Andreaco ,  Lars A. Eriksson ,  Charles W. Williams ,  Ronald Nutt

IPC: G01T3/06

CPC classification number: G01T1/1644 ,  A61B6/037 ,  G01T1/2928

Abstract: A detector for use in imaging applications includes at least one detector array, an array of photodetectors, and a continuous light guide disposed between the detectors and the photodetectors. The light guide is continuous over the entire area of the photodetectors and detectors. The thickness of the light guide is optimized based on the shape of the photodetector array. Each detector array includes a plurality of scintillator elements disposed in an M×N array, where “M” and “N” are independently selectable and are each at least one. A mechanism for maintaining the relative positions of the individual scintillator elements with respect to each other is provided. The retainer is further provided to enhance the separation between the individual detector arrays to define distinct boundaries between the position profiles of the scintillator arrays.

Abstract translation: 用于成像应用的检测器包括至少一个检测器阵列，光电检测器阵列，以及设置在检测器和光电探测器之间的连续光导。 导光体在光电检测器和检测器的整个区域上是连续的。 基于光电检测器阵列的形状优化光导的厚度。 每个检测器阵列包括设置在MxN阵列中的多个闪烁体元件，其中“M”和“N”可独立选择并且各自至少一个。 提供了用于保持各个闪烁体元件相对于彼此的相对位置的机构。 进一步提供保持器以增强各个检测器阵列之间的间隔，以限定闪烁体阵列的位置分布之间的不同边界。

公开(公告)号：US07601963B2

公开(公告)日：2009-10-13

申请号：US11830342

申请日：2007-07-30

Applicant: Mehmet Aykac ,  Ronald Grazioso

Inventor： Mehmet Aykac ,  Ronald Grazioso

IPC: G01T1/20

CPC classification number: G01T1/202 ,  G01T1/2008 ,  G01T1/2018

Abstract: A depth of interaction-sensitive crystal scintillation detector features crystal types that alternate in three-dimensional checkerboard fashion, each type having a different crystal decay time. One or more photosensors are disposed on each of at least two orthogonal surfaces. The scintillation detector provides improved depth of interaction resolution. The different crystal types are identified by pulse shape discrimination processing.

Abstract translation: 相互作用敏感的晶体闪烁检测器的深度具有以三维棋盘方式交替的晶体类型，每种类型具有不同的晶体衰减时间。 一个或多个光传感器被布置在至少两个正交表面中的每一个上。 闪烁检测器提供改善的相互作用分辨率深度。 通过脉冲形状识别处理识别不同的晶体类型。

公开(公告)号：US20090008562A1

公开(公告)日：2009-01-08

申请号：US11772909

申请日：2007-07-03

Applicant: Ronald Grazioso ,  Mehmet Aykac

Inventor： Ronald Grazioso ,  Mehmet Aykac

IPC: G01T1/20

CPC classification number: G01T1/1644 ,  A61B6/037 ,  G01T1/2002

Abstract: A detector is provided for nuclear medicine imaging. Scintillator pixels form an axial array and a transaxial array. A first photosensor is positioned along the axial array; and a second photosensor is positioned along the transaxial array, wherein the first photosensor and the second photosensor provide dual event localization for nuclear medicine imaging.

Abstract translation: 提供用于核医学成像的检测器。 闪烁体像素形成轴向阵列和横轴阵列。 第一光电传感器沿着轴向阵列定位; 并且第二光电传感器沿着轴向阵列定位，其中第一光电传感器和第二光电传感器为核医学成像提供双重事件定位。

公开(公告)号：US07737407B2

公开(公告)日：2010-06-15

申请号：US11772909

申请日：2007-07-03

Applicant: Ronald Grazioso ,  Mehmet Aykac

Inventor： Ronald Grazioso ,  Mehmet Aykac

IPC: G01T1/166 ,  G01T1/20

CPC classification number: G01T1/1644 ,  A61B6/037 ,  G01T1/2002

Abstract: A detector is provided for nuclear medicine imaging. Scintillator pixels form an axial array and a transaxial array. A first photosensor is positioned along the axial array; and a second photosensor is positioned along the transaxial array, wherein the first photosensor and the second photosensor provide dual event localization for nuclear medicine imaging.

Abstract translation: 提供用于核医学成像的检测器。 闪烁体像素形成轴向阵列和横轴阵列。 第一光电传感器沿着轴向阵列定位; 并且第二光电传感器沿着轴向阵列定位，其中第一光电传感器和第二光电传感器为核医学成像提供双重事件定位。

公开(公告)号：US07408164B2

公开(公告)日：2008-08-05

申请号：US10441682

申请日：2003-05-20

Applicant: Matthias J. Schmand ,  Lars A. Eriksson ,  Niraj K. Doshi ,  Mehmet Aykac ,  Ronald Nutt

Inventor： Matthias J. Schmand ,  Lars A. Eriksson ,  Niraj K. Doshi ,  Mehmet Aykac ,  Ronald Nutt

IPC: G01T1/20

CPC classification number: G01T1/2002 ,  G01T1/202

Abstract: A detector array including a plurality of scintillators for use in association with an imaging device. The detector array is provided for accurate determination of the location of the impingement of radiation upon an individual scintillator detector. An air gap is disposed between the scintillator elements, thereby increasing the packing fraction and overall sensitivity of the array. The amount of light transmitted down the scintillator element and the amount of light transmitted to adjacent elements is modified to optimize the identification of each element in a position profile map by adjusting the surface finish of the detector elements.

Abstract translation: 一种检测器阵列，包括用于与成像装置相关联的多个闪烁体。 检测器阵列被提供用于准确地确定辐射冲击位置在单独的闪烁体检测器上。 在闪烁器元件之间设置气隙，从而增加阵列的封装分数和整体灵敏度。 通过调整检测器元件的表面光洁度来修改向下闪烁体元件传输的光量和透射到相邻元件的光量，以优化位置分布图中每个元素的识别。

公开(公告)号：US07019297B2

公开(公告)日：2006-03-28

申请号：US10441681

申请日：2003-05-20

Applicant: Mehmet Aykac ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Charles W. Williams ,  Ronald Nutt

Inventor： Mehmet Aykac ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Charles W. Williams ,  Ronald Nutt

IPC: G01T1/202

CPC classification number: G01T1/202 ,  B33Y70/00 ,  B33Y80/00 ,  G01T1/2002

Abstract: A method for fabricating an array adapted to receive a plurality of scintillators for use in association with an imaging device. The method allows the creation of a detector array such that location of the impingement of radiation upon an individual scintillator detector is accurately determinable. The array incorporates an air gap between all the scintillator elements. Certain scintillators may have varying height reflective light partitions to control the amount of light sharing which occurs between elements. Light transmission is additionally optimized by varying the optical transmission properties of the reflective light partition, such as by varying the thickness and optical density of the light partitions. In certain locations, no light partitions exist, thereby defining an air gap between those elements. The air gap allows a large increase in the packing fraction and therefore the overall sensitivity of the array.

Abstract translation: 一种用于制造适于接收与成像装置相关联使用的多个闪烁体的阵列的方法。 该方法允许创建检测器阵列，使得能够精确地确定单个闪烁体检测器上的辐射冲击位置。 该阵列包括所有闪烁体元件之间的气隙。 某些闪烁体可以具有变化的高度反射光分区，以控制在元件之间发生的光共享的量。 通过改变反射光分区的光传输特性，例如通过改变光分区的厚度和光密度来另外优化透光。 在某些位置，不存在光分区，从而在这些元件之间限定气隙。 空气间隙允许包装分数大幅度增加，因此阵列的整体灵敏度增加。