专利检索 ap:("Redx Pharma PLC") AND inv:"Richard Armer" 第 1 页

1.

发明公开
PHARMACEUTICAL FORMULATION 审中-公开

公开(公告)号：US20240082244A1

公开(公告)日：2024-03-14

申请号：US18271913

申请日：2022-01-14

申请人： Redx Pharma PLC

发明人： Richard Armer , Marce De Matas

IPC分类号： A61K31/497 , A61K9/48

CPC分类号： A61K31/497 , A61K9/4825 , A61K9/4833 , A61K9/4866

摘要： This invention relates to pharmaceutical formulations and a method of making a pharmaceutical formulation. In particular, the invention relates to pharmaceutical formulations and a method of making a pharmaceutical formulation comprising Compound I and a diluent.

2.

发明申请
HETEROCYCLIC COMPOUNDS AS HEDGEHOG SIGNALING PATHWAY INHIBITORS 有权
标题翻译：杂环化合物作为HEDGEHOG信号途径抑制剂

公开(公告)号：US20160113928A1

公开(公告)日：2016-04-28

申请号：US14893691

申请日：2014-05-28

申请人： REDX PHARMA PLC

发明人： Richard Armer , Matilda Bingham , Inder Bhamra , Andrew McCarroll

IPC分类号： A61K31/502 , A61K45/06 , C07D471/04 , A61K31/501 , A61K31/5377 , C07D417/14 , A61K31/506 , C07D401/14 , A61K31/5025

CPC分类号： A61K31/502 , A61K31/501 , A61K31/5025 , A61K31/506 , A61K31/5377 , C07D237/30 , C07D401/14 , C07D417/14 , C07D471/04

摘要： This invention relates to novel compounds of formula (I). The compounds of the invention are hedgehog pathway antagonists. Specifically, the compounds of the invention are useful as Smoothened (SMO) inhibitors. The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of the Hedgehog pathway and SMO, for example cancer.

摘要翻译： 本发明涉及新的式（I）化合物。本发明的化合物是刺猬蛋白通路拮抗剂。具体地，本发明的化合物可用作平滑（SMO）抑制剂。本发明还考虑了该化合物用于治疗可通过抑制Hedgehog途径和SMO（例如癌症）治疗的病症的用途。

3.

发明授权
Heterocyclic compounds as hedgehog signaling pathway inhibitors 有权
标题翻译：杂环化合物作为刺猬蛋白信号通路抑制剂

公开(公告)号：US09579319B2

公开(公告)日：2017-02-28

申请号：US14893691

申请日：2014-05-28

申请人： Redx Pharma PLC

发明人： Richard Armer , Matilda Bingham , Inder Bhamra , Andrew McCarroll

IPC分类号： A61K31/502 , C07D237/30 , C07D401/14 , C07D471/04 , A61K31/501 , A61K31/5025 , A61K31/506 , A61K31/5377 , C07D417/14

CPC分类号： A61K31/502 , A61K31/501 , A61K31/5025 , A61K31/506 , A61K31/5377 , C07D237/30 , C07D401/14 , C07D417/14 , C07D471/04

摘要： This invention relates to novel compounds of formula (I). The compounds of the invention are hedgehog pathway antagonists. Specifically, the compounds of the invention are useful as Smoothened (SMO) inhibitors. The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of the Hedgehog pathway and SMO, for example cancer.

摘要翻译： 本发明涉及新的式（I）化合物。本发明的化合物是刺猬蛋白通路拮抗剂。具体地，本发明的化合物可用作平滑（SMO）抑制剂。本发明还考虑了该化合物用于治疗可通过抑制Hedgehog途径和SMO（例如癌症）治疗的病症的用途。