公开(公告)号：US20230242875A1

公开(公告)日：2023-08-03

申请号：US17920373

申请日：2021-04-14

申请人： RUICHUANG BIOTECH.CO., LTD.

发明人： Liming Yang ,  Zhiqiang Xiang ,  Qinghua Sun

IPC分类号： C12N5/078 ,  A61K35/17

CPC分类号： C12N5/0634 ,  A61K35/17 ,  C12N2501/515 ,  C12N2501/59 ,  C12N2500/90 ,  C12N2509/00 ,  C12N2501/2302

摘要： The present invention relates to a universal-type efficient in-vitro amplification method for multiple times of clinical feedback of allogenic DNT cells. In the method of the present invention, the amount of a T cell activator is phased down in a continuous culture process without the need for additional interleukin-4 or AB serum.