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公开(公告)号：US10517897B1
公开(公告)日：2019-12-31
申请号：US16574830
申请日：2019-09-18
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham , Sivan Elloul
IPC分类号： A61K35/18 , C07K14/705 , A61P17/00 , C12N5/078 , A61K39/395 , A61K38/19 , A61K35/12 , A61K39/00
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
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公开(公告)号：US10456421B2
公开(公告)日：2019-10-29
申请号：US15716141
申请日：2017-09-26
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham , Sivan Elloul
IPC分类号： A61K35/18 , A61K35/12 , A61K38/19 , A61K39/00 , A61K39/395 , C12N5/078 , A61P17/00 , C07K14/705
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
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3.发明申请公开(公告)号：US20190083540A1
公开(公告)日：2019-03-21
申请号：US16207568
申请日：2018-12-03
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham , Sivan Elloul
IPC分类号： A61K35/18 , A61K38/19 , A61K39/00 , A61K39/395 , A61P17/00 , C12N5/078 , A61K35/12 , C07K14/705
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
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4.发明申请公开(公告)号：US20180085402A1
公开(公告)日：2018-03-29
申请号：US15716141
申请日：2017-09-26
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham , Sivan Elloul
IPC分类号： A61K35/18 , A61K39/395 , A61K38/19 , A61K39/00 , C12N5/078
CPC分类号： A61K35/18 , A61K35/12 , A61K38/191 , A61K39/0011 , A61K39/3955 , A61K2039/505 , A61K2039/515 , A61P17/00 , C07K14/705 , C07K2319/00 , C12N5/0641 , C12N2510/00
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
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5.发明申请公开(公告)号：US20220072048A1
公开(公告)日：2022-03-10
申请号：US17528422
申请日：2021-11-17
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham
IPC分类号： A61K35/18 , A61K35/12 , A61K38/19 , A61K39/00 , A61K39/395 , C12N5/078 , A61P17/00 , C07K14/705
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating immune conditions. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having an autoimmune disease or inflammatory disease.
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6.发明申请公开(公告)号：US20200172868A1
公开(公告)日：2020-06-04
申请号：US16632119
申请日：2017-07-19
发明人： Tom Wickham , Tiffany F. Chen , Nathan Dowden , Robert Finberg , Robert J. Deans , John Round , Avak Kahvejian , Jordi Mata-Fink , Noubar B. Afeyan
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating an infectious disease. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having an infectious disease.
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公开(公告)号：US20200016209A1
公开(公告)日：2020-01-16
申请号：US16574830
申请日：2019-09-18
发明人： Avak Kahvejian , Jordi Mata-Fink , Robert J. Deans , Tiffany F. Chen , John Round , Noubar B. Afeyan , Torben Straight Nissen , Nathan Dowden , Tom Wickham , Sivan Elloul
IPC分类号： A61K35/18 , C07K14/705 , A61P17/00 , C12N5/078 , A61K39/395 , A61K39/00 , A61K38/19 , A61K35/12
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
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公开(公告)号：US20180344770A1
公开(公告)日：2018-12-06
申请号：US15932341
申请日：2018-02-16
发明人： Tom Wickham , Tiffany F. Chen , Xuqing Zhang , Carolyn Hudak , Jordi Mata-Fink , Sivan Elloul , Billy Law , Lenka Hoffman , Kristian Eric Teichert , Shamael Rabia Dastagir
IPC分类号： A61K35/18
CPC分类号： C12N5/0641
摘要： Described herein are novel preparations of functionalized erythroid cells and related compositions, reagents, and methods for use in human pharmaceutical and veterinary applications.
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公开(公告)号：US11020435B2
公开(公告)日：2021-06-01
申请号：US15932341
申请日：2018-02-16
发明人： Tom Wickham , Tiffany F. Chen , Xuqing Zhang , Carolyn Sayre , Jordi Mata-Fink , Sivan Elloul , Billy Law , Lenka Hoffman , Kristian Eric Teichert , Shamael Rabia Dastagir
IPC分类号： A61K35/18 , C12N5/078 , A61K39/385 , A61K39/00 , A61K38/17
摘要： Described herein are novel preparations of functionalized erythroid cells and related compositions, reagents, and methods for use in human pharmaceutical and veterinary applications.
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10.发明申请公开(公告)号：US20200172867A1
公开(公告)日：2020-06-04
申请号：US16632115
申请日：2017-07-19
发明人： Tom Wickham , Tiffany F. Chen , Torben Straight Nissen , Nathan Dowden , Robert J. Deans , John Round , Avak Kahvejian , Jordi Mata-Fink , Noubar B. Afeyan
摘要： The invention includes compositions and methods related to multimodal therapies, e.g., for treating cardiovascular diseases and metabolic disorders. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cardiovascular disease or metabolic disorder.
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