公开(公告)号：US20190077747A1

公开(公告)日：2019-03-14

申请号：US16085489

申请日：2017-03-17

申请人： Queen Mary University of London

发明人： Michael Cattel ,  Gleb Sukhorukov ,  Saroash Shahid ,  Dong Luo

IPC分类号： C07C279/26

摘要： The present invention provides a crystalline salt of chlorhexidine chloride having a spherical morphology under Scanning Electron Microscopy (SEM) comprising a chloride anion and a cation selected from the group consisting of calcium, sodium, potassium, magnesium, zinc, strontium or iron, processes for the preparation of the salt, compositions, pharmaceutical compositions and uses thereof in medicine. Also provided are crystalline forms of the salt and fibres comprising the same.

公开(公告)号：US11578035B2

公开(公告)日：2023-02-14

申请号：US16832248

申请日：2020-03-27

申请人： Queen Mary University of London

发明人： Michael Cattel ,  Gleb Sukhorukov ,  Saroash Shahid ,  Dong Luo

IPC分类号： C07C279/26 ,  A61P31/04

摘要： The present invention provides a crystalline salt of chlorhexidine chloride having a spherical morphology under Scanning Electron Microscopy (SEM) comprising a chloride anion and a cation selected from the group consisting of calcium, sodium, potassium, magnesium, zinc, strontium or iron, processes for the preparation of the salt, compositions, pharmaceutical compositions and uses thereof in medicine. Also provided are crystalline forms of the salt and fibres comprising the same.

公开(公告)号：US20200290956A1

公开(公告)日：2020-09-17

申请号：US16832248

申请日：2020-03-27

申请人： Queen Mary University of London

发明人： Michael Cattel ,  Gleb Sukhorukov ,  Saroash Shahid ,  Dong Luo

IPC分类号： C07C279/26

摘要： The present invention provides a crystalline salt of chlorhexidine chloride having a spherical morphology under Scanning Electron Microscopy (SEM) comprising a chloride anion and a cation selected from the group consisting of calcium, sodium, potassium, magnesium, zinc, strontium or iron, processes for the preparation of the salt, compositions, pharmaceutical compositions and uses thereof in medicine. Also provided are crystalline forms of the salt and fibres comprising the same.