公开(公告)号：US20240102933A1

公开(公告)日：2024-03-28

申请号：US18382949

申请日：2023-10-23

Applicant: Polyvalor, Limited Partnership

Inventor： Frederic Leblond ,  Francois Daoust ,  Sandryne David

IPC: G01N21/65

CPC classification number: G01N21/65 ,  A61B5/0075

Abstract: There is described a method for performing a Raman spectroscopy measurement on a sample. The method generally has sequentially illuminating an area of said sample with first and second excitation signals, said first excitation signal being slightly spectrally spaced-apart from said second excitation signal, resulting in said area sequentially emitting first and second emission signals; upon receiving said first emission signal, measuring a first intensity value being indicative of optical intensity of said first emission signal within at least a detection band; upon receiving said second emission signal, measuring a second intensity value being indicative of optical intensity of said second emission signal within said detection band; and performing said Raman spectroscopy measurement by comparing said first intensity value to said second intensity value.

公开(公告)号：US20200284657A1

公开(公告)日：2020-09-10

申请号：US16647867

申请日：2018-09-14

Applicant: Polyvalor, Limited Partnership

Inventor： Frederic Leblond ,  Karl St-Arnaud ,  Francois Daoust

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/06 ,  G01J3/28 ,  G01N21/65

Abstract: A system and method for imaging a sample using Raman spectrometry. Optical fibers having opposite first ends and second ends are arranged with the first ends and second ends in respective two-dimensional arrays. The two-dimensional arrays maintain relative positions of the optical fibers to one another from the first ends to the second ends in a way that the first end of each optical fibers of the bundle can simultaneously collect a corresponding Raman signal portion scattered from specific spatial coordinates of the area of the sample. The so-collected Raman signal portions are propagated towards the corresponding second end, from which are outputted and detected simultaneously using an array of detectors.

公开(公告)号：US11796475B2

公开(公告)日：2023-10-24

申请号：US17286304

申请日：2019-10-15

Applicant: Polyvalor, Limited Partnership

Inventor： Frederic Leblond ,  Francois Daoust ,  Sandryne David

IPC: G01J3/44 ,  G01N21/65 ,  A61B5/00

CPC classification number: G01N21/65 ,  A61B5/0075

Abstract: There is described a method for performing a Raman spectroscopy measurement on a sample. The method generally has sequentially illuminating an area of said sample with first and second excitation signals, said first excitation signal being slightly spectrally spaced-apart from said second excitation signal, resulting in said area sequentially emitting first and second emission signals; upon receiving said first emission signal, measuring a first intensity value being indicative of optical intensity of said first emission signal within at least a detection band; upon receiving said second emission signal, measuring a second intensity value being indicative of optical intensity of said second emission signal within said detection band; and performing said Raman spectroscopy measurement by comparing said first intensity value to said second intensity value.

公开(公告)号：US20210381983A1

公开(公告)日：2021-12-09

申请号：US17286304

申请日：2019-10-15

Applicant: Polyvalor, Limited Partnership

Inventor： Frederic Leblond ,  Francois Daoust ,  Sandryne David

IPC: G01N21/65

Abstract: There is described a method for performing a Raman spectroscopy measurement on a sample. The method generally has sequentially illuminating an area of said sample with first and second excitation signals, said first excitation signal being slightly spectrally spaced-apart from said second excitation signal, resulting in said area sequentially emitting first and second emission signals; upon receiving said first emission signal, measuring a first intensity value being indicative of optical intensity of said first emission signal within at least a detection band; upon receiving said second emission signal, measuring a second intensity value being indicative of optical intensity of said second emission signal within said detection band; and performing said Raman spectroscopy measurement by comparing said first intensity value to said second intensity value.

公开(公告)号：US11105682B2

公开(公告)日：2021-08-31

申请号：US16647867

申请日：2018-09-14

Applicant: Polyvalor, Limited Partnership

Inventor： Frederic Leblond ,  Karl St-Arnaud ,  Francois Daoust

IPC: G01J3/44 ,  G01J3/02 ,  G01J3/06 ,  G01J3/28 ,  G01N21/65

Abstract: A system and method for imaging a sample using Raman spectrometry. Optical fibers having opposite first ends and second ends are arranged with the first ends and second ends in respective two-dimensional arrays. The two-dimensional arrays maintain relative positions of the optical fibers to one another from the first ends to the second ends in a way that the first end of each optical fibers of the bundle can simultaneously collect a corresponding Raman signal portion scattered from specific spatial coordinates of the area of the sample. The so-collected Raman signal portions are propagated towards the corresponding second end, from which are outputted and detected simultaneously using an array of detectors.