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公开(公告)号：US10463668B2
公开(公告)日：2019-11-05
申请号：US15586058
申请日：2017-05-03
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61K38/13 , A61K31/5377 , A61K31/56 , A61P35/00 , A61P35/02 , A61P43/00 , A61K35/17 , A61K45/06 , A61K35/28
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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公开(公告)号：US20180078555A1
公开(公告)日：2018-03-22
申请号：US15586058
申请日：2017-05-03
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61K31/56 , A61K31/5377 , A61K38/13 , A61K45/06
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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公开(公告)号：US20200147084A1
公开(公告)日：2020-05-14
申请号：US16418590
申请日：2019-05-21
Applicant: Pharmacyclics LLC
Inventor： Joseph J. Buggy , Tarak D. Mody , John C. Byrd , Betty Y. Chang , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson
IPC: A61K31/519 , A61K45/06
Abstract: Described herein are methods and compositions comprising a covalent TEC family kinase inhibitor for use in adjuvant therapy, including adjuvant cancer therapy, vaccination and treatment of immune disorders and pathogenic infections.
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公开(公告)号：US20200009148A1
公开(公告)日：2020-01-09
申请号：US16582945
申请日：2019-09-25
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61P35/00 , A61P35/02 , A61P43/00 , A61K38/13 , A61K31/5377 , A61K31/56 , A61K35/17 , A61K45/06
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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公开(公告)号：US20240293408A1
公开(公告)日：2024-09-05
申请号：US18372398
申请日：2023-09-25
Applicant: Pharmacyclics LLC
Inventor： John C. BYRD , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61K31/5377 , A61K31/56 , A61K35/17 , A61K35/28 , A61K38/13 , A61K45/06 , A61P35/00 , A61P35/02 , A61P43/00
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/56 , A61K35/17 , A61K38/13 , A61K45/06 , A61P35/00 , A61P35/02 , A61P43/00 , A61K35/28
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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Patent Agency Ranking
公开(公告)号：US20180071293A1
公开(公告)日：2018-03-15
申请号：US15650830
申请日：2017-07-14
Applicant: Pharmacyclics LLC
Inventor： Joseph J. Buggy , Tarak D. Mody , Richard B. Love , John C. Byrd , Betty Y. Chang , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson
IPC: A61K31/519 , A61K45/06
CPC classification number: A61K31/519 , A61K45/06 , A61K2300/00
Abstract: Described herein are methods and compositions comprising a covalent TEC family kinase inhibitor for use in adjuvant therapy, including adjuvant cancer therapy, vaccination and treatment of immune disorders and pathogenic infections.
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公开(公告)号：US09795604B2
公开(公告)日：2017-10-24
申请号：US14523650
申请日：2014-10-24
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy Jo Johnson , David Miklos
IPC: A61K31/519 , A61K38/13 , A61K35/17 , A61K45/06 , A61K31/5377 , A61K31/56 , A61K35/28
CPC classification number: A61K31/519 , A61K31/5377 , A61K31/56 , A61K35/17 , A61K35/28 , A61K38/13 , A61K45/06 , A61K2300/00
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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公开(公告)号：US09717731B2
公开(公告)日：2017-08-01
申请号：US14070420
申请日：2013-11-01
Applicant: Pharmacyclics LLC
Inventor： Joseph J. Buggy , Tarak D. Mody , John C. Byrd , Betty Y. Chang , Jason A. Dubovsky , Natarajan Muthusamy , Amy Jo Johnson
IPC: A61K31/519 , A61N5/10 , A61K45/06
CPC classification number: A61K31/519 , A61K45/06 , A61K2300/00
Abstract: Described herein are methods and compositions comprising a covalent TEC family kinase inhibitor for use in adjuvant therapy, including adjuvant cancer therapy, vaccination and treatment of immune disorders and pathogenic infections.
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公开(公告)号：US20230097340A1
公开(公告)日：2023-03-30
申请号：US17730764
申请日：2022-04-27
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61K38/13 , A61K31/5377 , A61K31/56 , A61P35/00 , A61P35/02 , A61P43/00 , A61K35/17 , A61K45/06
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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公开(公告)号：US20210121463A1
公开(公告)日：2021-04-29
申请号：US16900624
申请日：2020-06-12
Applicant: Pharmacyclics LLC
Inventor： John C. Byrd , Jason A. Dubovsky , Natarajan Muthusamy , Amy J. Johnson , David Miklos
IPC: A61K31/519 , A61K38/13 , A61K31/5377 , A61K31/56 , A61P35/00 , A61P35/02 , A61P43/00 , A61K35/17 , A61K45/06
Abstract: Described herein are methods for treating and preventing graft versus host disease using ACK inhibitors. The methods include administering to an individual in need thereof an ACK inhibitor such as ibrutinib for treating and preventing graft versus host disease.
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