公开(公告)号：US20240181028A1

公开(公告)日：2024-06-06

申请号：US18513738

申请日：2023-11-20

申请人： Pfizer Inc.

发明人： Catherine Alex ,  Annaliesa Sybil Anderson ,  Bishwa Raj Bhetuwal ,  Zecheng Chen ,  Kaushik Dutta ,  Caitlyn Gallagher ,  Jianxin Gu ,  Isis Kanevsky ,  Jin-Hwan Kim ,  Justin Keith Moran ,  Suddham Singh ,  Naveen Surendran ,  Abhishek Ravindra Vartak ,  YuYing Yang

IPC分类号： A61K39/09 ,  A61K47/64

CPC分类号： A61K39/092 ,  A61K47/646

摘要： The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in Prevnar, Synflorix and/or Prevnar 13. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said novel immunogenic compositions.

公开(公告)号：US20240350608A1

公开(公告)日：2024-10-24

申请号：US18634326

申请日：2024-04-12

申请人： Pfizer Inc.

发明人： Bishwa Raj Bhetuwal ,  Kaushik Dutta ,  Jianxin Gu ,  Sunayana Kapil ,  Jin-Hwan Kim ,  Justin Keith Moran ,  Suddham Singh ,  YuYing Yang

IPC分类号： A61K39/09 ,  A61K39/00 ,  A61K39/385 ,  A61K47/64

CPC分类号： A61K39/092 ,  A61K47/646 ,  A61K39/385 ,  A61K2039/55516

摘要： The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.