公开(公告)号：US20190183858A1

公开(公告)日：2019-06-20

申请号：US16306466

申请日：2017-06-01

Applicant: PUSAN NATIONAL UNIVERSITY INDUSTRY UNIVERSITY COOPERATION FOUNDATION

Inventor： Yu Seok MOON ,  Ju Il KIM

IPC: A61K31/4015 ,  A61K31/352 ,  A61P9/10 ,  A23L33/10

Abstract: The present invention relates to: a pharmaceutical composition for preventing or treating LDL cholesterol-related diseases, containing a ribosome-binding preparation; a food composition; and a method for preventing or treating LDL cholesterol-related diseases by using the composition. According to the present invention, the ribosome-binding preparation selectively increases the expression of an LDL receptor in intestinal epithelial cells so as to promote LDL absorption in blood and tissue, such that LDL level in the blood can be reduced, thereby being useful for preventing or treating various LDL cholesterol-related diseases including LDL hypercholesterolemia, hyperlipidemia, hypertension and apoplexy.