公开(公告)号：US20200342960A1

公开(公告)日：2020-10-29

申请号：US16628976

申请日：2017-07-06

Applicant: PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Jay LIU ,  Myung Gi YI ,  Petar ZUVELA

IPC: G16C20/50 ,  G16C20/20 ,  G16B15/30 ,  G16C10/00

Abstract: Disclosed is a target-based drug screening method using inverse quantitative structure-(drug)performance relationships (QSPR) analysis and molecular dynamics simulation. The method includes modeling a molecular structure of a test compound group against a target molecule, obtaining a quantitative structure-(drug)performance relationships (QSPR) of the test compound group, acquiring the optimal pharmacophore of a novel target-based drug through a numerical inversion of the QSPR, and selecting drug candidates having a molecular structure similar to the optimum pharmacophore from the test compound group.

公开(公告)号：US20240358261A1

公开(公告)日：2024-10-31

申请号：US18646836

申请日：2024-04-26

Applicant: PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Byeong Il LEE ,  Myung Gi YI

IPC: A61B5/01 ,  A61B5/00

CPC classification number: A61B5/015 ,  A61B5/7264

Abstract: The present disclosure relates to a cervical body temperature change monitoring system and method, in which a cervical body temperature change can be monitored by measuring body temperatures of the cervical vertebra before and after treatment and analyzing the measurement results. A cervical body temperature change monitoring system may include: a cervical vertebral area processing unit that determines whether the cervical vertebra is recognized using at least one pressure sensor and performs segmentation on cervical vertebra recognition area to generate a plurality of segmented areas; a temperature distribution analysis unit that measures a body temperature in the cervical vertebra recognition area using at least one temperature sensor and generates a temperature distribution map; and a body temperature change measurement unit that derives a treatment effect by using the map.

公开(公告)号：US20240358260A1

公开(公告)日：2024-10-31

申请号：US18646830

申请日：2024-04-26

Applicant: PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Byeong Il LEE ,  Myung Gi YI

IPC: A61B5/01 ,  A61B5/00 ,  G06T7/11

CPC classification number: A61B5/015 ,  A61B5/004 ,  G06T7/11 ,  A61B2576/02 ,  G06T2207/30004

Abstract: The present disclosure relates to a body extremity temperature change monitoring system and method. More specifically, the present disclosure relates to a body extremity temperature change monitoring system and method, which can monitor a temperature change by recognizing a body extremity and measuring the body temperature of the recognized body extremity. The body extremity temperature change monitoring system comprises: an image data acquisition unit that acquires body extremity image data including a hand or a foot; a segmented area generation unit; and a body extremity temperature map generation unit that generates a body extremity temperature map using temperature data for each of the segmented areas, wherein the body extremity is defined to include base parts having a palm and a foot sole, and branch parts having fingers and toes.