公开(公告)号：US20220199217A1

公开(公告)日：2022-06-23

申请号：US17535474

申请日：2021-11-24

Applicant: POSTECH Research and Business Development Foundation

Inventor： Sung Min PARK ,  Seung Hyun LEE

IPC: G16H20/17 ,  G16H50/20 ,  G16H70/40

Abstract: A method of determining a continuous drug dose using reinforcement learning and a pharmacokinetic-pharmacodynamic model according to an embodiment of the present invention includes, measuring or estimating a patient's pharmacokinetic-pharmacodynamic model; training a reinforcement learning algorithm using drug infusion data and patient state data based on the pharmacokinetic-pharmacodynamic model; and automatically determining a continuous drug dose by the trained reinforcement learning algorithm.