公开(公告)号：US20240382582A1

公开(公告)日：2024-11-21

申请号：US18663339

申请日：2024-05-14

Applicant: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION

Inventor： Jae Sung PARK ,  Su Yeon KIM ,  Seung Ik OH ,  Chungmin HAN

IPC: A61K39/215 ,  A61K9/51 ,  A61K39/00 ,  A61P31/14 ,  C12N7/00

Abstract: The present invention relates to nanovesicles which express immunomodulatory proteins or targeting proteins, methods for preparing the same and uses thereof. More specifically, the present invention provides plasma membrane bleb-based nanovesicles which are prepared more homogeneously than existing plasma membrane bleb-based nanovesicles, by using cell lines expressing various immunomodulatory proteins or targeting proteins in the plasma membrane as materials, methods for preparing the nanovesicles, pharmaceutical compositions including the nanovesicles, methods for inducing immunity using the nanovesicles and methods for signal transduction or targeting using the nanovesicles.