-
公开(公告)号：US20220213540A1
公开(公告)日：2022-07-07
申请号：US17605640
申请日：2020-04-22
Inventor： Jeong Wook LEE , Gyoo Yeol JUNG , Chang Ha WOO , Sungho Jang , Giyoung SHIN
IPC: C12Q1/6862 , C12Q1/6876
Abstract: The present invention relates to a novel probe set for an isothermal one-pot reaction, and uses thereof and, particularly, provides a method for easily, accurately, and quickly diagnosing molecules, in particular, infection diseases, in the field, the method having a form applicable in the field on the basis of a nucleic acid sequence by using a one-pot reaction composition under an isothermal condition. If a molecular diagnostic platform according to the present invention is used, a target sequence can be quickly and accurately detected. Also, elements (reaction buffer, enzyme) needed in a diagnostic process using the present invention are much more simple and convenient than in a conventional antibody-based diagnosis, and, thus, the diagnostic process can be performed by a non-skilled person, and the sensitivity and speed of diagnosis can be increased, as all reactions are unified at a constant temperature without expensive equipment used in general nucleic-acid-based molecular diagnostic technology, and an amplification process is performed automatically during a reaction process.
-
公开(公告)号：US20250092451A1
公开(公告)日：2025-03-20
申请号：US18967805
申请日：2024-12-04
Inventor： Jeong Wook LEE , Gyoo Yeol JUNG , Chang Ha WOO , Sungho Jang , Giyoung SHIN
IPC: C12Q1/6862 , C12Q1/6832 , C12Q1/6876
Abstract: The present invention relates to a novel probe set for an isothermal one-pot reaction, and uses thereof and, particularly, provides a method for easily, accurately, and quickly diagnosing molecules, in particular, infection diseases, in the field, the method having a form applicable in the field on the basis of a nucleic acid sequence by using a one-pot reaction composition under an isothermal condition. If a molecular diagnostic platform according to the present invention is used, a target sequence can be quickly and accurately detected. Also, elements (reaction buffer, enzyme) needed in a diagnostic process using the present invention are much more simple and convenient than in a conventional antibody-based diagnosis, and, thus, the diagnostic process can be performed by a non-skilled person, and the sensitivity and speed of diagnosis can be increased, as all reactions are unified at a constant temperature without expensive equipment used in general nucleic-acid-based molecular diagnostic technology, and an amplification process is performed automatically during a reaction process.
-
Search Results
2
records
(took 0.017 seconds)
