公开(公告)号：US20170165020A1

公开(公告)日：2017-06-15

申请号：US15118354

申请日：2015-02-16

Applicant: POLYVALOR, LIMITED PARTNERSHIP

Inventor： Sylvain MARTEL

IPC: A61B34/00 ,  A61N2/00 ,  A61B5/00 ,  G01R33/38 ,  A61B8/08 ,  A61M31/00 ,  A61K49/18 ,  A61K41/00 ,  A61B5/055 ,  A61B6/00

CPC classification number: A61B34/73 ,  A61B5/055 ,  A61B5/4839 ,  A61B6/4258 ,  A61B6/504 ,  A61B8/0891 ,  A61B2034/732 ,  A61B2560/063 ,  A61K41/00 ,  A61K49/1827 ,  A61M31/005 ,  A61N2/004 ,  G01R33/38

Abstract: A method for navigating therapeutic, diagnostic or imaging agents in a vascular network or body cavity is introduced. The method is characterized by high directional gradients and a high magnetic field strength. The latter is used to saturate the magnetization of magnetic therapeutic agents such that when combined with high directional gradients, improved navigation of the magnetic therapeutic agents can be provided at various depths within a patient's body.

公开(公告)号：US20210161382A1

公开(公告)日：2021-06-03

申请号：US17167683

申请日：2021-02-04

Applicant: POLYVALOR, LIMITED PARTNERSHIP

Inventor： Sylvain MARTEL

IPC: A61B5/00 ,  A61N2/02 ,  A61B5/055 ,  A61K41/00 ,  G01R33/28 ,  G01R33/30

Abstract: A method for navigating therapeutic, diagnostic or imaging agents in a vascular network or body cavity is introduced. The method is characterized by high directional gradients and a high magnetic field strength. The latter is used to saturate the magnetization of magnetic therapeutic agents such that when combined with high directional gradients, improved navigation of the magnetic therapeutic agents can be provided at various depths within a patient's body.

公开(公告)号：US20180102206A1

公开(公告)日：2018-04-12

申请号：US15711436

申请日：2017-09-21

Applicant: POLYVALOR, LIMITED PARTNERSHIP

Inventor： Sylvain MARTEL ,  Ouajdi Felfoul

IPC: H01F7/06 ,  H01F7/02 ,  A61K41/00 ,  G01R33/00

CPC classification number: H01F7/064 ,  A61B34/70 ,  A61B34/73 ,  A61B2090/374 ,  A61K35/74 ,  A61K41/00 ,  A61K47/69 ,  A61K47/6901 ,  G01R33/0023 ,  H01F7/0273

Abstract: Applicants have discovered a novel apparatus and method to aggregate and displace a plurality of magneto-responsive entities (steerable self-propelled entities or SSPEs) in three dimensions using time-multiplexing. The apparatus for controlling aggregation of SSPEs in a body comprises at least three sets of magnetic field sources arranged in three axes for generating a controlled magnetic field and a controller connected to at least one of said magnetic field sources to create a three dimensional convergence point. The method for aggregating the entities can comprise using a first set and a second set of said magnetic field sources to generate opposed magnetic field gradients in each said set to cause aggregation of said magneto-responsive entities in two axes and wherein the controller is configured to reverse a direction of said magnetic field gradient in a third set of magnetic field sources in a third axis according to a first predetermined program.