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公开(公告)号：US10314895B2
公开(公告)日：2019-06-11
申请号：US15213596
申请日：2016-07-19
发明人： Eric Heinz Altermann , Graeme Trevor Attwood , Gregory Cook , Debjit Dey , Scott A Ferguson , Petrus Hendricus Janssen , William John Kelly , Zhanhao Kong , Suzanne Lambie , Sinead Christine Leahy , Dong Li , Duncan McMillan , Sharla McTavish , Diana Pacheco , Robert Starr Ronimus , Carrie Sang , Carl Yeoman
IPC分类号： C12N15/31 , C07K14/195 , C07K16/12 , A61K39/00 , C12N15/74
摘要： The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
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公开(公告)号：US10960063B2
公开(公告)日：2021-03-30
申请号：US16285008
申请日：2019-02-25
发明人： Eric Heinz Altermann , Graeme Trevor Attwood , Gregory Cook , Debjit Dey , Scott A. Ferguson , Petrus Hendricus Janssen , William John Kelly , Zhanhao Kong , Suzanne Lambie , Sinead Christine Leahy , Dong Li , Duncan McMillan , Sharla McTavish , Diana Pacheco , Robert Starr Ronimus , Carrie Sang , Carl Yeoman
IPC分类号： C12N15/31 , C07K14/195 , C07K16/12 , A61K39/00 , C12N15/74
摘要： The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminan-tium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynu-cleotides, antibodies, expression vectors, and host cells.
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公开(公告)号：US20170157225A1
公开(公告)日：2017-06-08
申请号：US15213596
申请日：2016-07-19
发明人： Eric Heinz ALTERMANN , Graeme Trevor Attwood , Gregory Cook , Debjit Dey , Scott A. Ferguson , Petrus Hendricus Janssen , William John Kelly , Zhanhao Kong , Suzanne Lambie , Sinead Christine Leahy , Dong Li , Duncan McMillan , Sharla McTavish , Diana Pacheco , Robert Starr Ronimus , Carrie Sang , Carl Yeoman
IPC分类号： A61K39/00
CPC分类号： A61K39/0001 , A61K2039/552 , C07K14/195 , C07K16/1267 , C12N15/74 , G01N2333/195
摘要： The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
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