公开(公告)号：US20180312488A1

公开(公告)日：2018-11-01

申请号：US16029850

申请日：2018-07-09

申请人： OTSUKA PHARMACEUTICAL CO., LTD.

发明人： Hiroshi SHIMIZU ,  Yoshikazu KAWANO ,  Shunpei ISHIKAWA ,  Yukitaka UEMATSU ,  Toshio SHINOHARA ,  Motohiro ITOTANI ,  Yoshikazu HARAGUCHI ,  Isao TAKEMURA ,  Atsunori KANESHIGE ,  Yuya NAKAI ,  Norimitsu HARIGUCHI ,  Yohei HAYASHI ,  Makoto MATSUMOTO

IPC分类号： C07D401/14 ,  C07D401/06 ,  C07D215/227

摘要： It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.

公开(公告)号：US20170253576A1

公开(公告)日：2017-09-07

申请号：US15506887

申请日：2015-08-28

申请人： OTSUKA PHARMACEUTICAL CO., LTD.

发明人： Hiroshi SHIMIZU ,  Yoshikazu KAWANO ,  Shunpei ISHIKAWA ,  Yukitaka UEMATSU ,  Toshio SHINOHARA ,  Motohiro ITOTANI ,  Yoshikazu HARAGUCHI ,  Isao TAKEMURA ,  Atsunori KANESHIGE ,  Yuya NAKAI ,  Norimitsu HARIGUCHI ,  Yohei HAYASHI ,  Makoto MATSUMOTO

IPC分类号： C07D401/14 ,  C07D401/06 ,  C07D215/227

CPC分类号： C07D401/14 ,  C07D215/227 ,  C07D401/06

摘要： It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.

公开(公告)号：US20190040039A1

公开(公告)日：2019-02-07

申请号：US16079713

申请日：2017-02-27

申请人： OTSUKA PHARMACEUTICAL CO., LTD.

发明人： Yoshikazu KAWANO ,  Hiroshi SHIMIZU ,  Shunpei ISHIKAWA ,  Isso TAKEMURA ,  Norimitsu HARIGUCHI ,  Miki MATSUBA ,  Makoto MATSUMOTO

IPC分类号： C07D401/12 ,  C07D211/44 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12 ,  C07D411/12 ,  C07D471/04

摘要： The purpose of the present invention is to provide a compound having excellent antibacterial activity against mycobacterium tuberculosis, multidrug-resistant tuberculosis bacteria, and/or non-tuberculous acid-fast bacteria. A compound represented by formula [I]: (in the formula, each symbol is as described in the attached specification), or a salt thereof can be used to diagnose, prevent, and/or treat tuberculosis.