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公开(公告)号：US20180344731A1
公开(公告)日：2018-12-06
申请号：US16057586
申请日：2018-08-07
IPC分类号： A61K31/496
CPC分类号： A61K31/496 , A61K31/4704 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1) wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
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公开(公告)号：US09387207B2
公开(公告)日：2016-07-12
申请号：US14637511
申请日：2015-03-04
IPC分类号： A61K31/496 , A61K31/4704 , A61K45/06
CPC分类号： A61K31/496 , A61K31/4704 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
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公开(公告)号：US20170224681A1
公开(公告)日：2017-08-10
申请号：US15494877
申请日：2017-04-24
IPC分类号： A61K31/496
CPC分类号： A61K31/496 , A61K31/4704 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1) wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
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公开(公告)号：US09006248B2
公开(公告)日：2015-04-14
申请号：US13932385
申请日：2013-07-01
IPC分类号： A61K31/497 , C07D401/00 , A61K31/496 , A61K45/06
CPC分类号： A61K31/496 , A61K31/4704 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
摘要翻译： 本发明涉及一种治疗患有与5-HT 1A受体亚型相关的中枢神经系统紊乱的患者的方法，其包含由式（1）表示的喹诺酮衍生物或其盐作为活性成分：其中， 喹诺酮骨架中3-和4-位之间的碳 - 碳键是单键或双键。
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公开(公告)号：US20200093823A1
公开(公告)日：2020-03-26
申请号：US16695777
申请日：2019-11-26
IPC分类号： A61K31/496 , A61K45/06
摘要： The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1) wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
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