公开(公告)号：US20220388955A1

公开(公告)日：2022-12-08

申请号：US17621137

申请日：2020-06-26

Applicant: ONO PHARMACEUTICAL CO., LTD.

Inventor： Akio WATANABE ,  Atsushi YOSHIDA ,  Yasuo HIROOKA ,  Michael G. YANG ,  Ning LI

IPC: C07D207/34 ,  A61K31/40 ,  C07D401/12 ,  A61K31/4439 ,  C07C233/76 ,  A61K31/167 ,  C07D231/12 ,  A61K31/415 ,  C07D233/70 ,  A61K31/4174 ,  C07D213/75 ,  A61K31/44 ,  C07D241/18 ,  A61K31/4965 ,  C07D487/04 ,  A61K31/519 ,  C07D213/56 ,  C07C323/29 ,  A61K31/145 ,  A61P35/00

Abstract: A drug containing, as an active ingredient, a compound having an antagonistic activity against an EP2 receptor in the prevention and/or treatment of a disease associated with the activation of an EP2 receptor, of formula (I-A): wherein all symbols have the same meanings as those described in the specification, or a pharmaceutically acceptable salt thereof.