公开(公告)号：US20180185502A1

公开(公告)日：2018-07-05

申请号：US15739375

申请日：2016-06-23

申请人： OHIO STATE INNOVATION FOUNDATION

发明人： Jon Robert PARQUETTE ,  Sriram SATAGOPAN ,  Yuan SUN ,  Fred Robert TABITA

IPC分类号： A61K47/64 ,  A61K47/54 ,  C21B13/00 ,  A61K47/69 ,  B01D53/62 ,  B01D53/86 ,  B01D53/88

CPC分类号： A61K47/64 ,  A61K47/542 ,  A61K47/6925 ,  B01D53/62 ,  B01D53/8671 ,  B01D53/88 ,  B01D2255/804 ,  B01D2255/90 ,  B01D2257/504 ,  B01D2258/06 ,  C12Y401/01039 ,  C12Y402/01001 ,  C21B13/0073 ,  Y02C10/04

摘要： Disclosed are nanostructures such as carboxysomes that encapsulate RubisCO and carbonic anhydrase to provide a protected environment to maximize CO2 assimilation. Conditions are disclosed were RubisCO can be sequestered into a variety of self-assembling nanotubes. The encapsulated protein was enzymatically active and was clearly associated with the nanotubes and removed from solution based on a number of criteria. These nanostructures were also found to enhance the stability of RubisCO toward proteases and other environmental factors. These structures can be used in scalable CO2 conversions and other processes.