公开(公告)号：US20240299526A1

公开(公告)日：2024-09-12

申请号：US18681132

申请日：2022-08-11

Applicant: Nutcracker Therapeutics, Inc.

Inventor： Samuel Deutsch ,  Daniel Frimannsson ,  Ole Haabeth ,  Pei-Ken Hsu

IPC: A61K39/12 ,  A61K39/00 ,  A61P31/14

CPC classification number: A61K39/12 ,  A61P31/14 ,  A61K2039/53 ,  C12N2770/20034

Abstract: The presently described and disclosed technology includes, in one example, a method, comprising: extracting a sequence of a spike protein of a first virus from a first non-human mammal that is previously exposed to an infection by the first virus; identifying a target antigen specific to the spike protein; and injecting an mRNA therapeutic comprising an mRNA encoding the target antigen into a human patient that has antibodies to a second virus.