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公开(公告)号:US11826463B2
公开(公告)日:2023-11-28
申请号:US17488650
申请日:2021-09-29
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
IPC: A61K9/68 , A23G4/08 , A23G4/10 , A23G4/06 , A23G4/12 , A23G4/20 , A61K47/26 , A61K31/05 , A61K31/192 , A61K31/352 , A61K47/61 , A61K36/185
CPC classification number: A61K9/0058 , A23G4/068 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20 , A61K31/05 , A61K31/192 , A61K31/352 , A61K36/185 , A61K47/26 , A61K47/61 , A23V2002/00
Abstract: The present invention relates to a chewing gum for mucosal delivery of cannabinoids, the chewing gum including water-soluble chewing gum ingredients and water-insoluble gum base, wherein the gum base has one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the water-soluble chewing gum ingredients include one or more sugar alcohols in an amount of 35-80% by weight of the chewing gum, and wherein the chewing gum has one or more cannabinoids.
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公开(公告)号:US11154496B2
公开(公告)日:2021-10-26
申请号:US16257914
申请日:2019-01-25
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
IPC: A61K9/68 , A61K47/61 , A61K31/05 , A61K31/192 , A61K31/352 , A61K36/185 , A61K47/32 , A23G4/06 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20
Abstract: The present invention relates to a chewing gum for mucosal delivery of cannabinoids, the chewing gum being formulated as an extruded chewing gum including water-soluble chewing gum ingredients mixed into water-insoluble gum base, wherein the gum base has one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the one or more elastomer plasticizers includes one or more polyvinyl acetate elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the chewing gum has one or more cannabinoids.
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公开(公告)号:US10925853B2
公开(公告)日:2021-02-23
申请号:US16386477
申请日:2019-04-17
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen , Helle Wittorff
IPC: A61K31/352 , A61K31/05 , A61K31/192 , A61K9/00 , A61K9/20
Abstract: The present invention relates to an oral tablet for delivery of cannabinoids to mucosal surfaces comprising a population of particles and one or more cannabinoids, the population of particles comprising a) directly compressible (DC) sugar alcohol particles and b) non-directly compressible (non-DC) sugar alcohol particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas.
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公开(公告)号:US20240065973A1
公开(公告)日:2024-02-29
申请号:US18493276
申请日:2023-10-24
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
CPC classification number: A61K9/0058 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20 , A61K31/352 , A23V2002/00
Abstract: A tableted chewing gum composition for oral administration of cannabinoids includes a plurality of particles, including a first population of particles having water-insoluble gum base and a second population of particles having water-soluble chewing gum ingredients. The composition constitutes at least two layers, where a first layer of the composition has water-insoluble gum base and a second layer of the composition, which is cohered to and adjacent to the first layer, has water-soluble chewing gum ingredients. The second layer is free of water-insoluble gum base, and the composition includes one or more cannabinoids.
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公开(公告)号:US11833117B2
公开(公告)日:2023-12-05
申请号:US17004648
申请日:2020-08-27
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
CPC classification number: A61K9/0058 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20 , A61K31/352 , A23V2002/00
Abstract: A tableted chewing gum composition for oral administration of cannabinoids includes a plurality of particles, including a first population of particles having water-insoluble gum base and a second population of particles having water-soluble chewing gum ingredients. The composition constitutes at least two layers, where a first layer of the composition has water-insoluble gum base and a second layer of the composition, which is cohered to and adjacent to the first layer, has water-soluble chewing gum ingredients. The second layer is free of water-insoluble gum base, and the composition includes one or more cannabinoids.
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公开(公告)号:US20220323349A1
公开(公告)日:2022-10-13
申请号:US17852892
申请日:2022-06-29
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
IPC: A61K9/68 , A61K36/185 , A61K31/352 , A61K47/26 , A61K31/192 , A61K47/40 , A61K31/05
Abstract: The present invention relates cannabinoid chewing gums with improved flavor perception. The cannabinoid chewing gums include water-soluble chewing gum ingredients and water-insoluble gum base, one or more cannabinoids with an off-note taste, one or more high intensity sweeteners in an amount of 0.05 to 0.9% by weight of the cannabinoid chewing gum that partly serves to mask the taste of said unbound cannabinoids, one or more flavoring ingredients in an amount of 0.01 to 5% by weight of the cannabinoid chewing gum that in combination with the one or more high intensity sweeteners partly serves to mask the taste of said unbound cannabinoids, wherein the one or more cannabinoids is located in close proximity with the one or more high intensity sweeteners as well as the one or more flavoring ingredients.
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公开(公告)号:US20210177748A1
公开(公告)日:2021-06-17
申请号:US16713580
申请日:2019-12-13
Applicant: NordicCan A/S
Abstract: The present invention relates in a first aspect to a fast disintegrating cannabinoid tablet, the tablet comprising a sugar alcohol composition comprising one or more sugar alcohol particles in an amount of at least 20% by weight of the tablet, a cannabinoid composition comprising one or more cannabinoids, and a disintegrant composition comprising one or more disintegrants operable to disintegrate the tablet within a period of 2 minutes or less in contact with oral saliva. In a second aspect, the invention relates to a modular tablet, wherein the tablet comprises a further tablet module that is different in composition.
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公开(公告)号:US20240065972A1
公开(公告)日:2024-02-29
申请号:US18490896
申请日:2023-10-20
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
IPC: A61K9/68 , A23G4/06 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20 , A61K31/05 , A61K31/192 , A61K31/352 , A61K36/185 , A61K47/26 , A61K47/61
CPC classification number: A61K9/0058 , A23G4/068 , A23G4/08 , A23G4/10 , A23G4/12 , A23G4/20 , A61K31/05 , A61K31/192 , A61K31/352 , A61K36/185 , A61K47/26 , A61K47/61 , A23V2002/00
Abstract: The present invention relates to a chewing gum for mucosal delivery of cannabinoids, the chewing gum including water-soluble chewing gum ingredients and water-insoluble gum base, wherein the gum base has one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the water-soluble chewing gum ingredients include one or more sugar alcohols in an amount of 35-80% by weight of the chewing gum, and wherein the chewing gum has one or more cannabinoids.
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公开(公告)号:US11253473B2
公开(公告)日:2022-02-22
申请号:US16289810
申请日:2019-03-01
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
IPC: A61K9/68 , A61K31/352 , A61K9/00 , A61K31/485 , A61K47/44 , A61K47/12 , A61K47/26 , A61K47/38 , A61K47/10 , A61K9/107
Abstract: The present invention relates to a method of producing a tableted chewing gum composition for oral administration of cannabinoids, the method comprises the steps of: i) feeding a gum composition comprising water-insoluble gum base into an extruder from one or more feeding inlets, optionally including additional ingredients, ii) pressurizing the gum composition in the extruder while controlling temperature and pressure of the gum composition, optionally including further ingredients from one or more feeding inlets, iii) extruding the gum composition through a die means, iv) cutting the extruded gum composition in a liquid filled chamber, thereby obtaining a first population of particles comprising water-insoluble gum base, v) including the first population of particles with a second population of particles comprising water-soluble chewing gum ingredients and one or more cannabinoids, the second population of particles being free of water-insoluble gum base, thereby obtaining a chewing gum composition and vi) tableting the chewing gum composition in a tablet pressing apparatus, thereby obtaining a tableted chewing gum composition.
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公开(公告)号:US11241413B2
公开(公告)日:2022-02-08
申请号:US16852133
申请日:2020-04-17
Applicant: NordicCan A/S
Inventor: Heidi Ziegler Bruun , Dorthe Schackinger Boesen , Ane Eriksen
Abstract: The present invention relates to a lozenge composition for controlled release of cannabinoids comprising; i) a master granule component comprising one or more solid particles and one or more cannabinoids reversibly associated with the one or more solid particles; and ii) an extragranular component blended with the master granule component comprising one or more extragranular sugar alcohols.
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