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公开(公告)号:US11155548B2
公开(公告)日:2021-10-26
申请号:US16498196
申请日:2018-03-27
Applicant: Noramco, LLC
Inventor: Jessica Cardot , Joshua Sasine , Paul Nichols
IPC: C07D489/02 , C07D471/08 , C07D489/04
Abstract: A method of recovering a highly pure hydrocodone base from an impure hydrocodone preparation includes contacting the impure hydrocodone preparation with a weak acid in water to form a solution and adding a strong base to the solution in an amount sufficient to precipitate the pure hydrocodone base product. A highly pure hydrocodone base comprises less than 0.0025 wt % codeinone.